Effects of Stressful Life Events on Patients with Recurrent Ahthous Ulcer.

SRRS를 이용한 재발성 아프타성 구내궤양 환자의 생활변화에 관한 연구

  • Ko, Myung-Yun (Department of Oral Medicine, School of Dentistry, Busan National University) ;
  • Kim, Young-Ae (Department of Oral Medicine, School of Dentistry, Busan National University) ;
  • Ok, Soo-Min (Department of Oral Medicine, School of Dentistry, Busan National University) ;
  • Heo, Jun-Young (Department of Oral Medicine, School of Dentistry, Busan National University) ;
  • Jeong, Sung-Hee (Department of Oral Medicine, School of Dentistry, Busan National University) ;
  • Ahn, Yong-Woo (Department of Oral Medicine, School of Dentistry, Busan National University)
  • 고명연 (부산대학교 치의학전문대학원 구강내과학 교실) ;
  • 김영애 (부산대학교 치의학전문대학원 구강내과학 교실) ;
  • 옥수민 (부산대학교 치의학전문대학원 구강내과학 교실) ;
  • 허준영 (부산대학교 치의학전문대학원 구강내과학 교실) ;
  • 정성희 (부산대학교 치의학전문대학원 구강내과학 교실) ;
  • 안용우 (부산대학교 치의학전문대학원 구강내과학 교실)
  • Received : 2012.11.11
  • Accepted : 2012.11.27
  • Published : 2012.12.30


Recurrent aphthous ulcer(RAU) is the most frequent form of oral ulceration with a prevalence in the general population ranging between 5% and 60%. The peak age of onset is between 10 and 19 years of age, and it can persist into adulthood and throughout the patient's lifespan, with no gender predilection. The disease is characterized clinically into three types: minor aphthous ulcer, major aphthous ulcer and herpeticform ulcers. The cause of RAU is unknown and thought to be multifactorial with many triggers or precipitating factors that include familial tendency or genetic predisposition, allergy, medications, hormones, stress or anxiety, and immunologic abnormalities. The need for consideration of psychological factors in the pathogenesis of oral disease has been increasingly acknowledged over the last decades and many studies have highlighted the psycho-social impact of oral conditions. In this study, we tried to evaluate the influence of emotional stress in RAU. There were thirty patients with a clinical diagnosis of RAU and other subjects who did not show any signs of systemic disorders include RAU. They are evaluated by using modified Holmes and Rahe's Social Readjustment Rating Scale (SRRS). As a result, a significantly higher level of stress was found in the RAU patients than the control group. Therefore it can be concluded that psychological stressors play an important role in the RAU.


Recurrent aphthous ulcer;Social readjustment rating scale (SRRS);Stressful life events


Supported by : 부산대학교병원


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