Should Male Circumcision be Advocated for Genital Cancer Prevention?

  • Morris, Brian J. (Molecular Medical Sciences, University of Sydney) ;
  • Mindel, Adrian (Sexual Health Medicine, Sydney Medical School, University of Sydney) ;
  • Tobian, Aaron A.R. (Department of Pathology, School of Medicine, Johns Hopkins University) ;
  • Hankins, Catherine A. (Amsterdam Institute for Global Health and Development and Department of Global Health, Academic Medical Centre, University of Amsterdam) ;
  • Gray, Ronald H. (Department of Pathology, School of Medicine, Johns Hopkins University) ;
  • Bailey, Robert C. (Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois) ;
  • Bosch, Xavier (Institut Catala d'Oncologia, L'Hospitalet de Llobregat) ;
  • Wodak, Alex D. (St. Vincent's Hospital)
  • Published : 2012.09.30


The recent policy statement by the Cancer Council of Australia on infant circumcision and cancer prevention and the announcement that the quadrivalent human papillomavirus (HPV) vaccine will be made available for boys in Australia prompted us to provide an assessment of genital cancer prevention. While HPV vaccination of boys should help reduce anal cancer in homosexual men and cervical cancer in women, it will have little or no impact on penile or prostate cancer. Male circumcision can reduce cervical, penile and possibly prostate cancer. Promotion of both HPV vaccination and male circumcision will synergistically maximize genital cancer prevention.


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