DOI QR코드

DOI QR Code

Improved Accuracy of Cytodiagnosis using the Kato Self-Collection Devise: the Usefulness of Smear Preparation in Liquid-based Cytology Methods

  • Okayama, Kaori (Department of Pathology, Faculty of Health Sciences, Kyorin University) ;
  • Okodo, Mitsuaki (Department of Pathology, Faculty of Health Sciences, Kyorin University) ;
  • Fujii, Masahiko (Department of Pathology, Faculty of Health Sciences, Kyorin University) ;
  • Kumagai, Tomoko (I LABO Cyto-STD Laboratory Co. Ltd.) ;
  • Yabusaki, Hiromi (I LABO Cyto-STD Laboratory Co. Ltd.) ;
  • Shiina, Yoshio (I LABO Cyto-STD Laboratory Co. Ltd.) ;
  • Iwami, Fumihiro (Department of Public Health, Faculty of Health Sciences, Kyorin University) ;
  • Teruya, Koji (Department of Public Health, Faculty of Health Sciences, Kyorin University) ;
  • Hatta, Kenmei (Juno and Vesta Clinic)
  • Published : 2012.09.30

Abstract

Object: In the present study, we compared the positive cytodiagnostic test rates with discrepancies using self-collection devices for cervical cancer screening. We made this survey to examine whether or not our self-smear preparation method using the Kato self-collection device contributed to an improved rate of detecting atypical cells compared with existing recommended preparation methods. Methods: Specimens were collected at 14 facilities handling self-collection methods, and samples were collected by a physician in 2 facilities. The chisquared test was performed using the SPSS ver. 20 statistical software to determine the relationships between the positive cytodiagnostic rate, specimen preparation methods, and self-collection devices. Results: Collecting cells using the Kato self-collection device and preparing liquid-based specimens, we obtained a significantly higher rate of positive cytodiagnosis and our results were equal to those obtained with the direct method. Conclusions: Taking into consideration increased needs for screening using the self-collection method in future, with even more improved test accuracy, a screening test that is acceptable to society needs to be established.

References

  1. Aoki D, Saito E, Tominaga E (2012). Cervical cancer screening. Gan To Kagaku Ryoho, 39, 23-6.
  2. Belinson J, Qiao YL, Pretorius R, et al (2001). Shanxi Province Cervical Cancer Screening Study: a cross-sectional comparative trial of multiple techniques to detect cervical neoplasia. Gynecol Oncol, 83, 439-44. https://doi.org/10.1006/gyno.2001.6370
  3. Belinson JL, Qiao YL, Pretorius RG, et al (2003). Shanxi Province cervical cancer screening study II: self-sampling for high-risk human papillomavirus compared to direct sampling for human papillomavirus and liquid based cervical cytology. Int J Gynecol Cancer, 13, 819-26. https://doi.org/10.1111/j.1525-1438.2003.13611.x
  4. Garcia F, Barker B, Santos C et al (2003). Cross-sectional study of patient- and physician-collected cervical cytology and human papillomavirus. Obstet Gynecol, 102, 266-72. https://doi.org/10.1016/S0029-7844(03)00517-9
  5. Laara E, Day NE, Hakama M (1987). Trends in mortality from cervical cancer in the Nordic countries: association with organised screening programmes, Lancet, 30, 1247-49.
  6. Mitchell MF, Tortolero-Luna G, Wright T et al (1996). Cervical human papillomavirus infection and intraepithelial neoplasia: a review. J Natl Cancer Inst Monogr, 21, 17-25.
  7. Noguchi M, Nakanishi M, Kato K (1982). Appraisal of a newly developed self-collection device for obtaining cervical specimens. Acta Cytol, 26, 633-35.
  8. Salmeron J, Lazcano-Ponce E, Lorincz A et al (2003). Comparison of HPV-based assays with Papanicolaou smears for cervical cancer screening in Morelos State, Mexico. Cancer Causes Control, 14, 505-12. https://doi.org/10.1023/A:1024806707399
  9. Sanchaisuriya P, Pengsaa P, Sriamporn S et al(2004). Experience with a self-administered device for cervical cancer screening by Thai women with different educational backgrounds. Asian Pac J Cancer Prev, 5, 144-50.

Cited by

  1. Comparative Assessment of a Self-sampling Device and Gynecologist Sampling for Cytology and HPV DNA Detection in a Rural and Low Resource Setting: Malaysian Experience vol.16, pp.18, 2016, https://doi.org/10.7314/APJCP.2015.16.18.8495
  2. Cervical cytology and human papillomavirus among asymptomatic healthy volunteers in Vientiane, Lao PDR vol.17, pp.1, 2017, https://doi.org/10.1186/s12885-017-3900-6