Improved Accuracy of Cytodiagnosis using the Kato Self-Collection Devise: the Usefulness of Smear Preparation in Liquid-based Cytology Methods

  • Okayama, Kaori (Department of Pathology, Faculty of Health Sciences, Kyorin University) ;
  • Okodo, Mitsuaki (Department of Pathology, Faculty of Health Sciences, Kyorin University) ;
  • Fujii, Masahiko (Department of Pathology, Faculty of Health Sciences, Kyorin University) ;
  • Kumagai, Tomoko (I LABO Cyto-STD Laboratory Co. Ltd.) ;
  • Yabusaki, Hiromi (I LABO Cyto-STD Laboratory Co. Ltd.) ;
  • Shiina, Yoshio (I LABO Cyto-STD Laboratory Co. Ltd.) ;
  • Iwami, Fumihiro (Department of Public Health, Faculty of Health Sciences, Kyorin University) ;
  • Teruya, Koji (Department of Public Health, Faculty of Health Sciences, Kyorin University) ;
  • Hatta, Kenmei (Juno and Vesta Clinic)
  • Published : 2012.09.30


Object: In the present study, we compared the positive cytodiagnostic test rates with discrepancies using self-collection devices for cervical cancer screening. We made this survey to examine whether or not our self-smear preparation method using the Kato self-collection device contributed to an improved rate of detecting atypical cells compared with existing recommended preparation methods. Methods: Specimens were collected at 14 facilities handling self-collection methods, and samples were collected by a physician in 2 facilities. The chisquared test was performed using the SPSS ver. 20 statistical software to determine the relationships between the positive cytodiagnostic rate, specimen preparation methods, and self-collection devices. Results: Collecting cells using the Kato self-collection device and preparing liquid-based specimens, we obtained a significantly higher rate of positive cytodiagnosis and our results were equal to those obtained with the direct method. Conclusions: Taking into consideration increased needs for screening using the self-collection method in future, with even more improved test accuracy, a screening test that is acceptable to society needs to be established.


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