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Various Aspects, Patterns and Risk Factors in Breast Cancer Patients of Balochistan

  • Baloch, Abdul Hameed (Department of Biotechnology and Informatics, BUITEMS) ;
  • Shuja, Jameela (Center for Nuclear Medicine and Radiotherapy (CENAR)) ;
  • Daud, Shakeela (Center for Advanced Molecular Biology (CAMB)) ;
  • Ahmed, Muneer (Center for Nuclear Medicine and Radiotherapy (CENAR)) ;
  • Ahmad, Adeel (Mayo hospital) ;
  • Tareen, Mehrullah (Center for Nuclear Medicine and Radiotherapy (CENAR)) ;
  • Khan, Farah (Center for Nuclear Medicine and Radiotherapy (CENAR)) ;
  • Kakar, Muhammad Azam (Department of Biotechnology and Informatics, BUITEMS) ;
  • Baloch, Dost Mohammad (Department of Biotechnology and Informatics, BUITEMS) ;
  • Kakar, Naseebullah (Department of Biotechnology and Informatics, BUITEMS) ;
  • Naseeb, Hafiz Khush (Center for Nuclear Medicine and Radiotherapy (CENAR)) ;
  • Ahmad, Jamil (Department of Biotechnology and Informatics, BUITEMS)
  • Published : 2012.08.31

Abstract

Purpose: Breast cancer is the commonest malignancy of females throughout the world with one million new cases each year. In Pakistan, the burden of breast cancer disease is high with late stage presentation being a common feature, more than half being stage III or stage IV. The objective of this study was to study various aspects, patterns and risk factors in breast cancer patients of Balochistan. Method: Present study was performed on 134 patients of breast cancer who were registered in CENAR. The patients were interviewed by providing a questionnaire. Informed consent was taken from all the patients who took part in this study after explanation of the study aims. Body mass index (BMI) was calculated andbiopsy reports were obtained from patients files. All the cases were classified with respect to age, gender, ethnic group (Baloch, Pashtoon, Punjabi, Afghani, Hazara) BMI, cancer type, cancer grade, hormonal status, side of the cancer, fertility and marital status. Results: Out of 134 patients, the most common ethnic group was Pashtoon with a total of 42 and the common age group was 41-50 years with a total of 51. Invasive ductal carcinoma (IDC) was the most common type, accounting for in 128 patients (95.5%) followed by invasive lobular carcinoma (ILC). Conclusion: Pashtoon was the most common ethnic group, IDC was common type and most of the patients had an ER/PR positive hormonal status.

Keywords

Breast cancer;Balochistan;hereditary cancer;CENAR cancer registry

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