- Volume 13 Issue 8
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Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Locoregionally Advanced Nasopharyngeal Carcinoma
- Yu, Hong-Sheng (Department of Oncology, the Affiliated Hospital of Medical College, Qingdao University) ;
- Wang, Xin (Department of Otorhinolaryngology-Head and Neck Surgery, The First Hospital of Jilin University) ;
- Song, Ai-Qin (Department of Oncology, the Affiliated Hospital of Medical College, Qingdao University) ;
- Liu, Ning (Department of Oncology, the Affiliated Hospital of Medical College, Qingdao University) ;
- Zhang, Wei (Department of Oncology, the Affiliated Hospital of Medical College, Qingdao University) ;
- Yu, Li (Department of Oncology, the Affiliated Hospital of Medical College, Qingdao University)
- Published : 2012.08.31
Objective: To compare the clinical effects of concurrent radiochemotherapy with those of radiotherapy in treating locally advanced nasopharyngeal carcinoma (Stage III~IVa). Methods: A total of 95 patients suffering from nasopharyngeal carcinoma (Stage III~IVa) were divided into two groups: concurrent radiochemotherapy (Group CCRT, n=49) and radiotherapy (Group RT, n=46). The two groups were both delivered conventional fractionated radiotherapy, while Group CCRT also received three cycles of PF (DDP+5-Fu) or PLF (DDP+5-Fu+CF) chemotherapy. Results: The complete remission rate and total remission rate of Group CCRT were higher than those of Group RT (
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