Effects of the Combination of Glucose, Chromium Picolinate, and Vitamin C on Lipid Metabolism in Steers

  • Lee, Hong-Gu (Department of Animal Science, Pusan National University) ;
  • Yin, Jin-Long (Department of Animal Science and Technology and Research Institute for Agriculture and Life Sciences, Seoul National University) ;
  • Xu, Cheng-Xiong (Department of Molecular Oncology, H Lee Moffitt Cancer Center) ;
  • Hong, Zhong-Shan (Department of Animal Science and Technology, Tianjin Agricultural University) ;
  • Lee, Zhe-Hu (Department of Animal Science and Technology and Research Institute for Agriculture and Life Sciences, Seoul National University) ;
  • Jin, Yong-Cheng (Department of Animal Science, Pusan National University) ;
  • Choi, Chang-Weon (Department of Animal Resources, Daegu University) ;
  • Lee, Do-Hyeung (GRRC, Hankyong University) ;
  • Kim, Kyoung-Hoon (National Livestock Research Institute, RDA) ;
  • Choi, Yun-Jaie (Department of Animal Science and Technology and Research Institute for Agriculture and Life Sciences, Seoul National University)
  • Received : 2011.03.21
  • Accepted : 2011.06.03
  • Published : 2011.12.01


This study was conducted to examine the effects of glucose, chromium picolinate (CrP), and vitamin C (Vit C) on lipid metabolism in Korean native steers fitted with indwelling catheters. A total of 12 Korean native steers were randomly allocated to the following treatments: 1) normal control diet, 2) same as 1) +250 g of glucose by intravenous (IV) infusion, 3) same as 2)+13.5 g CrP administered orally, and 4) same as 3)+2.52 g Vit C by IV infusion. Glucose, Vit C, and CrP treatments were administered for five days. At days 1 and 3, serum insulin was higher in treated animals than in those fed the control diet (p<0.05). Serum non-esterified fatty acid (NEFA) concentration in the steers on treatment 2), control+13.5 g CrP, was lower than those on other treatments at 90 min post-infusion on days 1 and 3 (p<0.05). The expression of peroxisome proliferator-activated receptor-${\gamma}$ (PPAR${\gamma}$)2, stearoyl-CoA desaturase-1 (SCD), fatty acid synthase (FAS), and glucose transporter type 4 (Glut 4) in the longissimus muscle of steers on treatment 2 was higher than those on other treatments. In conclusion, the results suggest that CrP is associated with the regulation of gene expression involved in adipogenesis.


Chromium Picolinate;Glucose;Lipid Metabolism;Steers;Vitamin C


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