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Association between the Polymorphism of the Fatty acid binding protein 5 (FABP5) Gene within the BTA 14 QTL Region and Carcass/Meat Quality Traits in Hanwoo

한우 14번 염색체 QTL 영역내 Fatty acid binding protein 5 유전자의 다형성과 도체 및 육질 형질과의 관련성 분석

  • Heo, Kang-Nyeong (National Institute of Animal Science, RDA) ;
  • Kim, Nam-Kuk (Gyeongnam Provincial Office, National Agricultural products Quality management Service (NAQS)) ;
  • Lee, Seung-Hwan (National Institute of Animal Science, RDA) ;
  • Kim, Nam-Young (National Institute of Animal Science, RDA) ;
  • Jeon, Jin-Tae (Gyeongsang National University) ;
  • Park, Eung-Woo (Coopreration & Governance Unit Research Policy Planning Division Research Policy Bureau, RDA) ;
  • Oh, Sung-Jong (National Institute of Animal Science, RDA) ;
  • Kim, Tae-Hun (National Institute of Animal Science, RDA) ;
  • Seong, Hwan-Hoo (National Institute of Animal Science, RDA) ;
  • Yoon, Du-Hak (Kyungpook National University)
  • 허강녕 (농촌진흥청 국립축산과학원) ;
  • 김남국 (국립농산물품질관리원 경남지원) ;
  • 이승환 (농촌진흥청 국립축산과학원) ;
  • 김남영 (농촌진흥청 국립축산과학원) ;
  • 전진태 (경상대학교) ;
  • 박응우 (농촌진흥청 연구정책국) ;
  • 오성종 (농촌진흥청 국립축산과학원) ;
  • 김태헌 (농촌진흥청 국립축산과학원) ;
  • 성환후 (농촌진흥청 국립축산과학원) ;
  • 윤두학 (경북대학교)
  • Received : 2011.03.18
  • Accepted : 2011.05.19
  • Published : 2011.08.31

Abstract

The aim of this study was to evaluate the association between economic traits of Korean cattle (Hanwoo) and genetic variation in fatty acid binding protein 5 (FABP5) gene within QTL region of carcass weight and marbling score traits on BTA 14. We sequenced for detection of single nucleotide polymorphism (SNP) with 24 unrelated Hanwoo samples and identified four SNPs (-1141A>G, 949A>G, 969A>G and 1085C>G). Relationship between the genotypes of 583 Hanwoo individuals by PCR-RFLP and economic traits were analyzed by the mixed regression model implemented in the ASReml program. As the result of statistical analysis, SNP1 (-1141A>G) showed significant effect (p<0.003) on marbling score (MS) and SNP2 (949A>G) showed significant effect (p<0.034) on eye muscle area (EMA). Further studies are required to validate the significant SNPs in a bigger population, but the SNPs (-1141A>G and 949A>G) of FABP5 could be a genetic marker to estimate molecular breeding value (MEBV) for carcass traits in Hanwoo.

Keywords

Hanwoo;FABP5;SNP;PCR-RFLP

Acknowledgement

Supported by : 농촌진흥청

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