Pancreatic Lipase Inhibitory and Antioxidant Activities of Zingiber officinale Extracts

생강 추출물의 pancreatic lipase 저해 및 항산화 활성

  • Received : 2010.12.06
  • Accepted : 2011.04.15
  • Published : 2011.06.30


Ginger (Zingiber officinale) is a well-known herb that is widely consumed as spice for the flavoring of foods. As part of our continuing search for bioactive materials, the in vitro pancreatic lipase inhibition and antioxidant properties of an aqueous ethanolic extract of Z. officinale were investigated. The total phenolic content was determined using a spectrophotometric method. The antioxidant efficacies of the extract was studied with radical scavenging assays using DPPH and $ABTS^+$ radicals. Further more, the antiobesity effect of the extract was evaluated by porcine pancreatic lipase assay. In particularly, the pancreatic lipase inhibitory activity of the ethyl acetate (EtOAc)-soluble portion from Z. officinale was significantly higher than that of the other solvent-soluble portions. The results suggest that Z. officinale may have therapeutic potential that may be useful in development of an anti-obesity agent or its precursors.


Zingiber officinale;pancreatic lipase inhibition;antioxidant activity;DPPH;$ABTS^+$


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