Reliability of Quantitative Sensory Testing Using Current Perception Thresholds in the Mandibular Nerve Area

하악신경영역에서 전류인지역치를 이용한 정량적 감각신경 검사의 재현성 조사

  • Choi, Hee-Hun (Department of Oral Medicine and Institute of Dental Science, School of Dentistry, Dankook University) ;
  • Kim, Mee-Eun (Department of Oral Medicine and Institute of Dental Science, School of Dentistry, Dankook University) ;
  • Kim, Ki-Suk (Department of Oral Medicine and Institute of Dental Science, School of Dentistry, Dankook University)
  • 최희훈 (단국대학교 치과대학 구강내과학교실.치의학연구소) ;
  • 김미은 (단국대학교 치과대학 구강내과학교실.치의학연구소) ;
  • 김기석 (단국대학교 치과대학 구강내과학교실.치의학연구소)
  • Received : 2011.02.22
  • Accepted : 2011.04.28
  • Published : 2011.06.30


Current Perception Threshold (CPT) using Neurometer($Neurometer^{(R)}$ CPT/C) is thought as one of easy and noninvasive QST(qunatitative sensory testing) tools for A${\beta}$, A${\delta}$ and C fibers within a relatively short time. However, conflicts about its reliability still exist. This study aimed to evaluate the reliability of CPTs evaluation and find a way to increase its reliability. Two examiners separately tested CPTs at each side of the mandibluar nerve areas for ten healthy male adults (average age of 22.4 years) three times with an intervals of a week during three weeks. Mean CPTs were compared between the right and left sides of the mandibular nerve area and between the three examinations on the each side. While CPTs at 2000 Hz(A${\beta}$ fiber) showed statistically significant side differences in all three examinations (p<0.05), significant side difference was found in only one examination at 250 Hz(A${\delta}$ fiber) and no difference at 5 Hz(C fiber). Comparing CPTs on the each side of the mandibular nerve area, all examinations at all sensory nerve fibers showed the least CPTs at the 1st examinations. CPTs at 250 Hz(A${\delta}$ fiber) and 5 Hz(C fiber) were significantly different between the first and the following examinations (p<0.05) and there was no significant difference between 2nd and 3rd examinations. The results of this study indicated that CPTs at 250 Hz(A${\delta}$ fiber) and 5 Hz(C fiber) are reliable but CPTs at 2000 Hz(A${\beta}$ fiber) is not appropriate for evaluation of side differences in the mandibular nerve area. In addition, it is suggested that repeated examination be helpful to increase reliability of the CPT evaluation.


quantitative sensory testing(QST);mandibular nerve;Neurometer;current perception threshold(CPT);reliability


  1. Karas ND, Boyd SB, Sinn DP. Recovery of neurosensory function following orthognathic surgery. J Oral Maxillofac Surg 1990;48:124-34.
  2. Shy ME, Frohman EM, So YT et al. Quantitative sensory testing: report of the therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2003;60:898-904.
  3. Rolke R, Magerl W, Campbell KA et al. Quantitative sensory testing: a comprehensive protocol for clinical trials. European Journal of Pain 2006;77-88.
  4. Pigg M, Baad-Hansen L, Svensson P, Drangsholt M, List T. Reliability of intraoral quantitative sensory testing(QST). Pain 2010;148:220-226.
  5. Rene Caissie. Quantitative Method to Evaluate the Functionality of the Trigeminal Nerve. J Oral Maxillofac Surg. 2007;65:2254-2259.
  6. Masson EA, Boulton AJ. The Neurometer: validation and comparison with conventional tests for diabetic neuropathy. Diabet Med 1991;8:S63-6.
  7. Taylor DN, Wallace JI, Masdeu JC. Perception of different frequencies of cranial transcutaneous electrical nerve stimulation in normal and HIV-positive individuals. Percept Mot Skills 1992;74:259-64.
  8. Raj PP, Chado HN, Angst M et al. Painless electrodiagnostic current perception threshold and pain tolerance threshold values in CRPS subjects and healthy controls: a multicenter study. Pain Pract 2001;1:53-60.
  9. Katims JJ, Rouvelas P, Sadler BT, Wesely SA. Current perception threshold: reproducibility and comparison with nerve conduction in evaluation of carpal tunnel syndrome. Trans Am Soc Artif Intern Organs 1989;35:280-4.
  10. Kiso T, Nagakura Y, Toya T et al. Neurometer Measurement of Current Stimulus Threshold in Rats. J Pharmacol Exp Ther 2001;297:352-6.
  11. 이영철, 안용우, 고명연, 박준상. 측두하악장애 환자에서의 전류인지역치와 동통내성역치. 대한구강내과학회지 2004;29; 41-50.
  12. 허준영, 태일호, 고명연, 안용우. 삼차신경통 환자에서 저출력레이저 조사에 따른 전류인지역치의 변화효과. 대한구강내과학회지 2008;33;97-103.
  13. 임현대, 이정현, 이유미. 치아임플란트 시술 후 삼차신경에서의 전류인지역치에 대한 연구. 대한구강내과학회지 2007;32;187-200.
  14. Kim HS, Kho HS, Kim YK, Lee SW, Chung SC. Reliability and Characteristics of Current Perception Thresholds in the Territory of the Infraorbital and Inferior Alveolar Nerves. J Orofac Pain 2000;14:286-92.
  15. Lerner TH, Goldstein GR, Hittelman E. Quantitative sensory nerve conduction threshold (sNCT) evaluation of the trigeminal nerve at the mental foramen area. J Prosthet Dent 2000;84:103-7.
  16. Caissie R, Landry PE, Paquin R, Champigny MF, Berthod F. Quantitative method to evaluate the functionality of the trigeminal nerve. J Oral Maxillofac Surg 2007;65:2254-9.
  17. Takekuma K, Ando F, Niino N, Shimokata H. Age and gender differences in skin sensory threshold assessed by current perception in community-dwelling Japanese. J Epidemiol 2000;10:S33-8.
  18. American Association of Electrodiagnostic Medicine (AAEM), Equipment and Computer Committee. Technology review: The neurometer currentperception threshold(CPT). Muscle Nerve 1999;22:523-531.<523::AID-MUS16>3.0.CO;2-1