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Recent Advances in Cancer Cachexia

암성 악액질의 최신 지견

  • Choi, Sang-Gyu (Department of Radiation Oncology, Dankook University College of Medicine)
  • 최상규 (단국대학교 의과대학 방사선종양학과)
  • Received : 2010.10.27
  • Accepted : 2011.01.12
  • Published : 2011.02.28

Abstract

Purpose: The study was aimed to review and understand the meaning of cancer cachexia. Methods: Using the keywords "cachexia" and "cancer cachexia" 30 oncology research published from 1974 to 2009 were selected for the review. Results: The mechanism of cancer cachexia has not been fully understood, but various pathogenesis appears to be involved in the development cachexia including altered metabolism of carbohydrate, lipid, and protein associated with cytokines and hormone. As a result, muscle strength, food intake and resting energy expenditure (REE) are reduced. Most medications for the treatment of cachexia show debating results except some drugs such as megace. Supportive care including nutritional education, nursing care, and social support are found another effective treatment options. Conclusion: The results of this study would help oncology nurses to understand the mechanism of cancer cachexia and its management.

Acknowledgement

Supported by : 단국대학교

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