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선학초 추출물의 미백활성

김동희;안봉전;이진영
Kim, Dong-Hee;An, Bong-Jeun;Lee, Jin-Young

  • 투고 : 2011.10.13
  • 심사 : 2011.11.02
  • 발행 : 2011.12.31

초록

선학초 추출물을 기능성 화장품 소재로 활용하기 위하여 미백효과를 검증하였다. 세포 내 tyrosinase 저해활성 측정결과 선학초 에탄올 추출물 $500{\mu}g/mL$에서 42%의 저해활성을 나타내었다. 이는 선학초 추출물이 세포 내 tyrosinase 발현을 억제시킴으로서 멜라닌 합성 또한 저해 하는 것임을 확인 할 수 있었다. 선학초 추출물의 단백질 발현과 mRNA 발현 억제효과를 검토한 결과 선학초 열수 및 에탄올 추출물을 처리한 B16F10군에서는 tyrosinase protein의 발현이 처리하지 않은 군보다 감소함을 확인할 수 있었다. 결과적으로 선학초 추출물의 미백효능을 확인할 수 있었으며, 식품 및 화장품의 기능성 소재로 이용이 가능할 것으로 판단된다.

키워드

미백활성;선학초

참고문헌

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피인용 문헌

  1. Inhibitory effect of melanin synthesis using organic solvent extracts from Scolopendra subspinipes mutilans vol.52, pp.1, 2014, https://doi.org/10.7852/jses.2014.52.1.1
  2. Leaf Extract on the UV-Induced Photoaging-Related Ion Channel, ORAI1, and the Enzymes Tyrosinase and Elastase vol.40, pp.1, 2015, https://doi.org/10.1111/jfbc.12171

과제정보

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