Association Study Between the Polymorphisms of Exostosin-1 Gene and Economic Traits in Hanwoo

한우 Exostosin-1 유전자의 SNP 탐색 및 경제형질 관련성 분석

  • Kim, Bum-Soo (Animal Genomics & Bioinformatics Division, National Institute of Animal Science, R. D. A.) ;
  • Kim, Nam-Kuk (Animal Genomics & Bioinformatics Division, National Institute of Animal Science, R. D. A.) ;
  • Lee, Seung-Hwan (Animal Genomics & Bioinformatics Division, National Institute of Animal Science, R. D. A.) ;
  • Cho, Yong-Min (Green Growth & Future Strategy Team, R. D. A.) ;
  • Heo, Kang-Nyeong (Animal Genomics & Bioinformatics Division, National Institute of Animal Science, R. D. A.) ;
  • Park, Eung-Woo (Coopreration & Governance Unit Research Policy Planning Division Research Policy Bureau, R. D. A.) ;
  • Yang, Boo-Keun (Department of Animal Resources Science, Kangwon National University) ;
  • Yoon, Du-Hak (Animal Genomics & Bioinformatics Division, National Institute of Animal Science, R. D. A.)
  • 김범수 (농촌진흥청 국립축산과학원) ;
  • 김남국 (농촌진흥청 국립축산과학원) ;
  • 이승환 (농촌진흥청 국립축산과학원) ;
  • 조용민 (농촌진흥청 기획조정관실) ;
  • 허강녕 (농촌진흥청 국립축산과학원) ;
  • 박응우 (농촌진흥청 연구정책국) ;
  • 양부근 (강원대학교 동물생명과학대학 동물자원과학) ;
  • 윤두학 (농촌진흥청 국립축산과학원)
  • Received : 2010.08.11
  • Accepted : 2010.12.02
  • Published : 2011.02.28


The aim of this study was to identify the polymorphism on exostosin-1 (EXT1) gene and to associate with economic traits in Hanwoo (Korean cattle). We sequenced for detection of single nucleotide polymorphism (SNP) with 24 unrelated individuals and identified four SNPs (T272196A, C272359T, G290964A and A302092G). Relationship between the genotypes of 583 Hanwoo individuals by PCR-RFLP and economic traits were analyzed by general linear model. In EXT1 gene, there were four SNPs associated with economic traits such as eye muscle area breeding value, marbling score breeding value, backfat and thickness breeding value (p<0.05 to p<0.01). In conclusion, this study indicates an important role of EXT1 gene in determining the meat quality or economic characteristics in Hanwoo.




Supported by : 농촌진흥청


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