Electrochemical Determination of GABA using a 3-D Nanoporous Gold Thin Film

3차원 구조의 다공성 금 박막을 이용한 GABA의 전기화학적 측정

  • Pyo, Su-Hyun (Interdisiciplinary Program of interated Biotechnology, Sogang University) ;
  • Lee, Jin-Ho (Department of Chemical & Biomolecular Engineering, Sogang University) ;
  • Oh, Byeung-Keun (Interdisiciplinary Program of interated Biotechnology, Sogang University)
  • 표수현 (서강대학교 바이오융합기술 협동과정) ;
  • 이진호 (서강대학교 공과대학 화공생명공학과) ;
  • 오병근 (서강대학교 바이오융합기술 협동과정)
  • Received : 2011.08.22
  • Accepted : 2011.08.30
  • Published : 2011.10.10


We fabricated a novel simple and rapid method of three dimensional nanoporous gold thin film (NPGF) onto a Au substrate using electrochemical deposition method. The NPGF-modified electrode analysis by scanning electron microscope and reveals the formation of nanopores, approximately 30~50 nm in diameter. differential pulse voltammetry was measured for the determination of ${\gamma}$-aminobutiric acid in the concentration range of ($10{\sim}100{\mu}M$ using a NPGF. The high sensitivity feature of NPGF is expected to be applied for real sample biosensor applications.


nanoporous thin film;differential pulse voltammetry;${\gamma}$-aminobutiric acid;electrochemical deposition


Supported by : 한국연구재단, 한국산업기술진흥원


  1. K.-Y. Syu, C.-L. Lin, H.-C. Huang, and J.-K. Lin, J. Agric. Food Chem., 56, 7637 (2008). https://doi.org/10.1021/jf801795m
  2. D. L. Crittenden, M. Chebib, and M. J. T. Jordan, J. Phys. Chem. A, 109, 4195 (2005). https://doi.org/10.1021/jp050320a
  3. C.-H. Oh and S.-H. Oh, J. Medi. Food, 7, 19 (2004). https://doi.org/10.1089/109662004322984653
  4. D. J. Laurie and W. Wisden, Int. Rev. Cytol., 213, 1 (2002).
  5. D. L. Crittenden, M. Chebib, and M. J. T. Jordan, J. Phys. Chem. A, 108, 203 (2004). https://doi.org/10.1021/jp036700i
  6. A. J. Shaha, F. Crespib, and C. Heidbrederb, Journal of Chromatography B, 781, 151 (2002). https://doi.org/10.1016/S1570-0232(02)00621-9
  7. S. Dong and Y. Wang, Electroalalysis, 1, 99 (1989). https://doi.org/10.1002/elan.1140010203
  8. W. A. El-Said, J.-H. Lee, B.-K. Oh, and J.-W. Choi, E. Chem. Commun., 12, 1756 (2010).
  9. A. J. Bard and L. R. Faulkner, Electrochemical Methodes, 2nd ed, Wiley New York, 452 (2001).