The Biological Activities of Extracts and Fractions of Herbal Plants

수종의 한약재 분획물의 생리활성 효과

  • Kim, Jeong-Hwan (Dept. of Oriental Rehabilitation Medicine, College of Oriental Medicine, Woo-Suk University) ;
  • Ko, Youn-Seok (Dept. of Oriental Rehabilitation Medicine, College of Oriental Medicine, Woo-Suk University)
  • 김정환 (우석대학교 한의과대학 한방재활의학과교실) ;
  • 고연석 (우석대학교 한의과대학 한방재활의학과교실)
  • Received : 2010.12.10
  • Accepted : 2010.12.27
  • Published : 2011.01.30

Abstract

Objectives : This study was conducted to identify the antimicrobial anti-oxidative and tyrosinase inhibitory effect of three kinds of herbal plants, Polygonum cuspidatum, Chelidonii herba, Pharbitis nil L. naturally grown across the nation. Methods : To investigate in vitro anti-oxidative activity assay, antimicrobial effect and tyrosinase inhibitory activity, MeOH 80% extract, n-hexane, chloroform, ethyl acetate, n-butanol and water fractions of herbal plants were tested by diphenylpicrylhydrazyl(DPPH) method. Results : Bsutanol fractions of each plants showed about 90% on anti-oxidative effect. In case of tyrosinase activity, ethlyacetate fraction of Polygonum cuspidatum showed a potent inhibition effect. In the antimicrobial effect, ethylacetate fraction of Polygonum cuspidatu, hexane fractions of Chelidonii herba and the methanol 80% extracts of Pharbitis nil L. exhibited inhibition effect significantly. Conclusions : In MeOH 80% extracts, we couldn't found any extracts or fractions which have antimicrobial, anti-oxidative and tyrosinase inhibitory activity, however ethylacetate fractions of Polygonum cuspidatum showed effects commonly in these three assay system.

Keywords

Biological activities;Polygonum cuspidatum;Chelidonii herba;Pharbitis nil L;Anti-oxidative

Acknowledgement

Supported by : 우석대학교

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