Gender Differences in the Diurnal Rhythm of Salivary Cortisol in Adolescents : Area under the curve analysis

청소년의 성별에 따른 Cortisol 분비의 일주기 차이 : 반복측정에 따른 Area Under the Curve 분석법 사용

  • Lee, Sang-Kwan (Dept. of Inernal Medicine and Neuroscience, College of Oriental Medicine, Won-Kwang University)
  • Published : 2010.12.30


Purpose : This study investigated the diurnal rhythm of cortisol in male and female adolescents. Methods : Salivary cortisol was examined in 52 normally developing subjects aged 13 to 14 years. Subjects provided saliva samples at 08:00h, 12:00h, 16:00h and 20:00h. Results : Males and females showed similar pattern of cortisol, which elevated cortisol in the morning and decreased in the evening. There were no differences of gender at 08:00h, 12;00h and 20:00h. There were also not difference between males and females using an area under the curve analysis. Conclusions : The same diurnal cortisol rhythm were found in male and female adolescents. Further research is needed to examine differences of gender in cortisol awakening response.


Supported by : 원광대학교


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