Comparison of Clinical Symptoms between Early and Late Onset Depression in Elderly Depressive Patients in Korea

한국의 노인우울증 환자에서 조발성 우울증과 만발성 우울증의 임상증상의 비교

  • Park, Ki-Hong (Department of Psychiatry, Korea University College of Medicine) ;
  • Lee, Hwa-Young (Department of Psychiatry, Korea University College of Medicine) ;
  • Ham, Byung-Joo (Department of Psychiatry, Korea University College of Medicine) ;
  • Lee, Min-Soo (Department of Psychiatry, Korea University College of Medicine)
  • 박기홍 (고려대학교 의과대학 신경정신과학교실) ;
  • 이화영 (고려대학교 의과대학 신경정신과학교실) ;
  • 함병주 (고려대학교 의과대학 신경정신과학교실) ;
  • 이민수 (고려대학교 의과대학 신경정신과학교실)
  • Received : 2010.06.24
  • Accepted : 2010.08.04
  • Published : 2010.08.31


Objectives : Clinical differences between elderly patients with early and late onset depression have been described although these have been inconsistent. We aimed to compare differences of clinical symptoms using the 17 items Hamilton Rating Scale for Depression(HAM-D-17) between two groups. Methods : Data of 175 elderly patients with a diagnosis of major depressive disorder according to DSM-IV from January 2005 to November 2009 were collected. Seventy five patients were early onset depression and one hundred patients were late onset depression. Depressive symptoms were assessed by the 17-item Hamilton Rating Scale for depression. Results : There were some differences in HAM-D-17 scores between early and late onset depression. Early onset depression patients scored significantly higher in retardation(t = 2.41, p = 0.017) and somatic symptoms( general)(t = 2.37, p = 0.019) than late onset depression patients. Conclusion : We concluded that early onset depression patients have more severe psychomotor retardation and general somatic symptoms than late onset depression patients in Korea. Because of some limitations of this study, further investigations will be needed to validate this study results.


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