Investigating of Nitrosamines in Small tributary rivers, Sewage Tretment Plants and Drinking Water Treatment Plants

하천수 및 상하수도처리공정에서의 니트로사민류 조사

  • Kim, Gyunga (Water Quality Institute, Busan Water Authority) ;
  • Roh, Jaesoon (Water Quality Institute, Busan Water Authority) ;
  • Bin, Jaehun (Water Quality Institute, Busan Water Authority) ;
  • Kim, Changwon (Department of Environmental Engineering, Pusan National University)
  • 김경아 (부산광역시 상수도사업본부 수질연구소) ;
  • 노재순 (부산광역시 상수도사업본부 수질연구소) ;
  • 빈재훈 (부산광역시 상수도사업본부 수질연구소) ;
  • 김창원 (부산대학교 환경공학과)
  • Received : 2009.11.06
  • Accepted : 2010.03.08
  • Published : 2010.05.30


This study was investigated nine nitrosamines in small tributary rivers, sewage treatment plants (STPs) and drinking water treatment plants. They are N-nitrosodimethylamine (NDMA), N-nitrosomethylethylamine (NMEA), N-nitrosodiethylamine (NDEA), N-nitrosopyrrolidine (NPYR), N-nitrosodi-n-propylamine (NDPA), N-nitrosomorpholine (NMOR), N-nitrosopiperidine (NPIP), N-nitrosodi-n-butylamine (NDBA) and N-nitrosodiphenylamine (NDPHA). The nine nitrosamines were analyzed by gas chromatography mass spectrometry (GC/MS) using solid phase extraction (SPE) with a coconut charcoal cartridge. Among the nine nitrosamines, NDMA, NMEA, NDEA, NDPA NDBA and NDPHA were detected in small tributary rivers and sewage tretment plants. In small tributary rivers, NDMA, NMEA, NDEA, NDPA, NDBA and NDPHA were obtained as ND~16.4 ng/L, ND~17.7 ng/L, ND~102.4 ng/L, ND~455.4 ng/L, ND~330.1 ng/L and ND~161.0 ng/L, respectively. Also NDMA, NMEA, NDEA, NDPA and NDBA were investigated ND~821.4 ng/L, 22.5~55.4 ng/L, 53.2~588.5 ng/L, ND~56.6 ng/L and ND~527.9 ng/L in STPs, respectively. In drinking water treatment plants, NMEA and NDEA concentration were increased to as high as 38.8 ng/L after ozonation process. However nitrosamines were decreased subsequent biological activated carbon (BAC) treatment process. It was supposed that nitrosamines were formed by $O_3$ oxidation and were removed by biodegradation of BAC.



  1. 국가환경정보센터(2009).
  2. 김승현, 유이종(2002). NDMA 새로운 도전. 대한환경공학회지, 24(4), pp. 743-74.
  3. 김종오, 김동수(2006). N-Nitrosodimethylamine(NDMA) 생성에 관한 예측과 비교연구. 대한환경공학회지, 28(4), pp. 402-406.
  4. 미국 캘리포니아주 보건국(2009).
  5. 미국 캘리포니아주 환경보건 위해성 평가기관(2009).
  6. 미국 환경보호국(2009).
  7. 미국 환경보호국(2009).
  8. 세계보건기구(2009).
  9. 손미혜, 박희정, 신정혜, 성낙주(2004). 멸치젓갈의 인공소화시 N-Nitrosamine 생성과 돌연변이의 상관성. J. Korea. soc. Food Sci. Nutr., 33(9), pp. 1560-1565.
  10. 안윤주, 남선화, 이재관(2008). 수계 유출가능성이 있는 유해화학물질 분류화. 수질보전 한국물환경학회지, 24(2), pp. 247-259.
  11. 유이종(2008). Monitoring and controlling of new disinfection by products: nitrosamines and emerging contaminants from the world largest MF/RO/UV plant. 다항목 동시수질분석 4개국 국제세미나 관련 자료집, 한국수자원공사, 한국물환경학회, pp. 139-156.
  12. Andrzejewski, P., Kasprzyk-Hordern, B., and Nawrocki, J. (2005). The hazard of N-nitrosodimethylamine(NDMA) formation during water disinfection with strong oxidants. Desalination, 176, pp. 7-45.
  13. Andrzejewski, P., Kasprzyk-Hordern, B., and Nawrocki, J. (2007). The hazard of N-nitrosodimethylamine(NDMA) formation during water disinfection with ozone. Water Res., submitted.
  14. Andrzejewski, P. and Kulik, N. (2007). The hazard of N-nitrosamines formation during short chain secondary amines(DMA, MEA and DEA) reactions with catalyzed and non-catalyzed hydrogenperoxide. Proc. of 10th International Conference on Environmental Science and Technology (10CEST 2007), submitted.
  15. Asami, M., Oya, M., and Kosaka, K. (2009). A nationwide survey of NDMA in raw and drinking water in Japan. Science of the Total Environment, 407, pp. 3540-3545.
  16. Charrois, J. W. A., Arend, M. W., Froese, K. L., and Hrudey, S. E. (2004). Detecting N-nitrosamines in drinking water at nanogram per liter levels using ammonia positive chemical ionization. Environ. Sci. Technol., 38(18), pp. 4835-4841.
  17. Choi, J. and Valentine, R. L. (2002). Formation of N-nithosodimethylamine (NDMA) from reaction of monochloroamine : a new disinfection by-product, Water Res., 36(4), pp. 817-824.
  18. Choi, J. and Valentine, R. L. (2003). N-nitrosodimethylamine formation by free-chlorine-enhanced nitrosation of dimethylamine. Environ. Sci. Technol., 37, pp. 4871-4876.
  19. Dutra, C. B., Andrade, R., Reyes, F. G. R., and Rath, S. (2006). Determination of volatile N-Nitrosamines in sausages by HS-SPME-GC-TEA. Toxicology Letters, 164S, S274-275, pp. 22-13.
  20. Fleming, E. C., Pennington, J. C., Wachob, B. G., Howe, R. A., and Hill, D. O. (1996). Removal of N-nitrosodimethylamine from waters using physical-chemical techniques. Journal of Hazardous Materials, 51, pp. 151-164.
  21. Gavinelli, M., Fanelli, R, Bonfanti, M., Davoli, E., and Airoldi, L. (1988). Volatile nitrosamines in foods and beverages: preliminary survey of the Ita- lian market. Bull. Environ. Contam. Toxicol., 40, pp. 41-46.
  22. Gerecke, A. C. and Sedlak, D. L. (2003). Precursors of N-nitrosodimethylamine in natural waters. Environ. Sci. Technol., 37, pp. 1331-1336.
  23. Hotchkiss, J. H. (1989). Preformed N-nitroso compounds in foods and beverages. Cancer Surv., 8, pp. 295-321.
  24. Jobb, D. B., Hunsinger, R., Meresz, O., and Taguchi, V. Y. (1992). in Proceedings of the Fifth National Conference on Drinking Water, Winnipeg, Manitoba, Canada.
  25. Krauss, M., Longree, P., Dorusch, F., Ort, C., and Hollender, J. (2009). Occurrence and removal of N-nitrosamones in wastewater tretment plants. Water Research, 43(17), pp. 4381-4391.
  26. Lee, C., Schmidt, C., Yoon, J., and von Gunten, U. (2007). Oxidation of N-Nitrosodimethylamine precursors with ozone and chlorine dioxide: kinetics and effect on NDMA formation potential. Environ. Sci. Technol., 41, pp. 2056-2063.
  27. Mitch, W. A. and Sedlak, D. L. (2002). Formation of N-nitrosodimethylamine(NDMA) from dimethylamine during chlorination. Environ. Sci. Technol., 36, pp. 588-595.
  28. Mitch, W. A., Sharp, J. O., Trussell, R. R., Valentine, R. L., Alvarez-Cohen, L., and Sedlak, D. L. (2003). N-Nitrosodimethylamine(NDMA) as a drinking water contaminant: a review. Environ Eng Sci., 20, pp. 389-404.
  29. Oh, M. C., Oh, C. K., Yang, T. S., and Kim, S. H. (2004). The Content of N-Nitrosamine in import Fishes. The Korean Journal of Culinary Research, 10(2), pp. 30-37.
  30. Oya, M., Kosaka, K., Asami, M., and Kunikane, S. (2008). Formation of N-nitrosodimethylamine (NDMA) by ozonation of dyes and related compounds. Chemosphere, 73, pp. 1724-1730.
  31. Schmidt, C. K. and Brauch, H. J. (2008). N,N-Dimethylsulfamide as Precursor for N-Nitrosodimethylamine (NDMA) Formation upon Ozonation and its Fate During Drinking Water Treatment. Environ. Sci. Technol., 42, pp. 6340-6346.
  32. Schreiber, M. and Mitch, W. A. (2006). Nitrosamine Formation Pathway Revisited: The importance of chloramine speciation and dissolved oxygen. Environ. Sci, Technol., 40, pp. 6007-6014.
  33. Sedlak, D. L., Deeb, R. A., Hawley, E. L., Mitch, W. A., Durbin, T. D., Mowbray, S., and Carr, S. (2005). Sources and fate of nitrosodimethylamine and its precursors in municipal wastewater tretment plants. Water Environ. Res., 77(1), pp. 32-39.
  34. Spectrum Laboratories Inc. (2009).
  35. Tateishi, H., Kitamoto, Y., and Miyata, M. (2008). Occurrence and behaviour of N-nitrosodimethylamine(NDMA) in source water and drinking water treatment process. Proceedings of 59th annual conference of Japan Water Works Association, pp. 562-563(in Japanese).
  36. Tricker, A. R., Spiegelhalder, B., and Preussmann, R. (1989). Environmental Exposure to Preformed Nitroso Compounds. Cancer Surv., 8, pp. 207-239.
  37. World Health Organization (2008). N-Nitrosodimethylamine in drinking-water. Background document for development of WHO Guidelines for Drinking-water Quality.
  38. Yurchenko, S. and Molder, U. (2005). N-Nitrosodimethylamine analysis in Estonian beer using positive-ion chemical ionization with gas chromatography-mass spectrometry. Food Chem., 89, pp. 455-463.
  39. Zhao, Y. Y., Boyd, J. M., Woodbeck, M., Andrews, R. C., Qin. F., Hrudey, S. E., and Li, X. F. (2008). Formation of N-Nitrosamines from Eleven Disinfection Treatments of Seven Different Surface Waters. Environ. Sci. Technol., 42(13), pp. 4857-4862.