- Volume 48 Issue 4
Development of Anti-Wrinkle Agent from Nelumbo nucifera Root Extract
연근 추출물에서 주름개선 소재의 개발
- Kim, Hee Jin (Department of Pharmaceutical Engineering, Inje University) ;
- Kim, Tagon (Department of Pharmaceutical Engineering, Inje University) ;
- Kang, Whan Yul (Amaranth Cosmetics) ;
- Baek, Hyun (Amaranth Cosmetics) ;
- Cheon, Hae Young (Amaranth Cosmetics) ;
- Kim, Bo Young (Amaranth Cosmetics) ;
- Kim, Donguk (Department of Pharmaceutical Engineering, Inje University)
- 김희진 (인제대학교 제약공학과) ;
- 김타곤 (인제대학교 제약공학과) ;
- 강환열 (아마란스화장품) ;
- 백현 (아마란스화장품) ;
- 전혜영 (아마란스화장품) ;
- 김보영 (아마란스화장품) ;
- 김동욱 (인제대학교 제약공학과)
- Received : 2010.02.22
- Accepted : 2010.03.24
- Published : 2010.08.31
In this research, root extracts of Nelumbo nucifera was tested to see the possibility for functional cosmetic agent. 70-100% ethanol was used as solvent and nuciferin was confirmed as active component. To test cosmetic effect of root extracts of Nelumbo nucifera, safety effect(MTT assay), anti-wrinkle effect(elastase inhibition assay) and antioxidation effect(DPPH free radical scavenging assay) were measured. When 100% ethanol was used as extracting solvent, cell viability was over 80% at
Supported by : 한국산업기술평가원
- KDA Textbook Editiong Board, Dermatology, 5th ed., Ryo Mook Gak, Seoul(2008).
- Korea Food and Drug Administration, http://www.kfda.go.kr/index.html.
- Elsner, P. and Mailbach, H. I., Cosmeceuticals and Active Cosmetics, 2nd ed., Taylor & Francis, New York, NY(2005).
- Lee, K. H. and Park, S. N., "Antioxidative Activities and Antiaging Effects of Geranium nepalense Extracts," J. Soc. Cosmet. Scientists Korea, 34(1), 25-35(2008).
- Yang, H. J. and Park, S. N., "Component Analysis and Study on Anti-elastase Activity of Equisetum arvense Extracts (II)," J. Soc. Cosmet. Scientists Korea, 33(3), 139-144(2007).
- Sim, G. S., Kim, J. H., Lee, D. H., Lee, B. C., Lee, G. S. and Pyo, H. B., "The Inhibition fo UVA-induced Matrix Metalloproteinase-1 in Human Dermal Fibroblasts and the Improvement of Skin Elasticity by Cirsium setidens Extract," J. Soc. Cosmet. Scientists Korea, 33(3), 181-187(2007).
- Kim, D. H., Choi, H. K., Cho, S. C., Kook, M. C. and Park, C. S., "Enhancement of Antioxidant and Anti-aging Activities fo Spirulina Extracts," J. Soc. Cosmet. Scientists Korea, 34(3), 225-231(2008).
- Pharmacognosy Researchers, Modernpharmacognosy, Hak Chan Publishing, Seoul(2000).
- Park, J. C., Functional Food and Oriental Medicine, Hyoilbooks, Seoul(2007).
- Association of Official Analytical Chemists, A.O.A.C., Official Methods of Analysis, 15th ed., Washington DC.(1990).
- Mosmann, T., "Rapid Colorimetric Assay for the Cellular Growth and Survival Application to Proliferation and Cytotoxic Assay," J. Immun Method, 65, 55-62(1983). https://doi.org/10.1016/0022-1759(83)90303-4
- Kim, H. J., "Development of Functional Cosmetic Agent from Nelumbo nucifera," Master Thesis, Inje University, Gimhae, Gyongnam(2009).
- Park, S. K., Hong, S.-K., Kim, H. J., Kim, B. Y., Kim, T. G., Kang, J. S. and Kim, D., "Cosmetic Effect of Angelica gigas Nakai Root Extracts," Korean Chem. Eng. Res., 47, 553-557(2009).
- Kim, J. Y., Yang, H. J., Lee, K. H., Jeon, S. M., Ahn, Y. J., Won, B. R. and Park, S. N., "Antioxidative and Antiaging Effects of Jeju Native Plant Extracts (II)," J. Soc. Cosmet. Scientists Korea, 33(3), 165-173(2007).