The Experiences of Thyroid Cancer Patients Receiving Radioactive Iodine Therapy

갑상선암환자의 방사성요오드 치료 경험 분석

  • Received : 2010.11.29
  • Accepted : 2010.12.17
  • Published : 2010.12.31


The purpose of this study was to investigate the perceived difficulties during both pre-treatment period and admission period for radioactive iodine therapy (RAIT), the level of information about RAIT provided by medical staffs and the satisfaction of RAIT process in thyroid cancer patients receiving RAIT. Participants were 165 thyroid cancer patients, who had total thyroidectomy and had been offered RAIT. The data were collected using structured questionnaire and open-ended questions and analyzed by descriptive statistics and content analysis. The most frequent perceived difficulties of RAIT was associated with thyroid specific symptoms during both pre-RAIT period and RAIT admission period(38.2% vs 43.0%). The rating of RAIT information provided by medical staffs was evaluated as over moderate level(mean $3.63{\pm}0.80$). The RAIT process satisfaction was investigated as moderate level(mean $6.43{\pm}2.21$). the satisfaction of RAIT was the highest in medical attention and coping procedure (mean $7.64{\pm}2.37$) however it was the lowest in adequacy of RAIT information(mean $5.67{\pm}2.78$). Thus the nursing intervention program for thyroid cancer patient undergoing RAIT should be developed to support needs of thyroid cancer patients related to thyroid specific symptoms and to improve patients' understanding about RAIT procedure so that patients have competence to participate in therapeutic activities efficiently.


Thyroid cancer;Radioactive iodine therapy (RAIT);Information;Satisfaction


Supported by : 한국연구재단


  1. 이승훈, 김태용, 류진숙, 공경엽, 김원배, 김성철, 홍석준, 송영기, "1개 병원 갑상선 암환자 특성의 추이분석", 대한내분비학회지, 제23권, 제1호, pp.35-43, 2008.
  2. 김원배, 김태용, 권혁상, 문원진, 이재복, 최영식, 김석기, 김선욱, 정기욱, 백정환, 김병일, 박도준, 동규,최준호, 정재훈, 정혜승, 김정한, 남기현, 장항석, 정 웅윤, 홍순원, 홍석준, 이정현, 이가희, 조영석, 강호철, 송민호, 박진우, 윤종호, 강성준, 이광우, "갑상선결절 및 암 진료권고안", 대한내분비학회지, 제22권, 제3호, pp. 157-187, 2007.
  3. 김병일, "방사성옥소 격리치료의 방사선피폭과 규제", 제46차 대한핵의학회 춘계학술대회 연수 교육, pp.21-26, 2007.
  4. 정재훈, "갑상선 분화암의 수술 후 방사성요오드 투여를 위한 전처치 기간", 대한내분비학회지, 제21권, 제 1호, pp. 90, 2006.
  5. 김영순, "I131치료에 대한 정보교육이 갑상선암 환자의 불안과 면역반응에 미치는 영향", 부산대학교 대학원 박사학위논문, 2006.
  6. Luster, M., Clarke, S. E., Dietlein, M., Lassmann, M., Lind, P., Oyen, W. J., Tennvall, J., & Bombardieri, E., "Guidelines for radioiodine therapy of differentiated thyroid cancer", European Journal of Nuclear Medicine and Molecular Imaging, Vol. 35, No. 10, pp.1941-1959, 2008.
  7. Hay, I. D., "Selective use of radioactive iodine in the postoperative management of patients with papillary and follicular thyroid carcinoma", Journal of Surgical Oncology, Vol. 94, No. 8, pp. 692-700, 2006.
  8. Sprague, B. L., Andersen, S. W., Trentham-Dietz, A., "Thyroid cancer incidence and socioeconomic indicators of health care access", Cancer Causes Control, Vol. 19, No. 6, pp. 585-593, 2008.
  9. Dominguez, L. J., Bevilacqua, M., Dibella, G., Barbagallo, M., "Diagnosing and managing thyroid disease in the nursing home", Journal of American Medical Directors Association, Vol. 9, No 1, pp. 9-17, 2008.
  10. Winbladh, A., & Järhult, J., "Fate of the non-operated, non-toxic goitre in a defined population", The British Journal of Surgery, Vol. 95, No. 3, pp. 338-343, 2008.
  11. Nishihara, E., Ohye, H., Amino, N., Takata, K., Arishima, T., Kudo, T., Ito, M., Kubota, S., Fukata, S., & Miyauchi, A., "Clinical characteristics of 852 patients with subacute thyroiditis before treatment", Internal Medicine, Vol. 47, No. 8, pp. 725-729, 2008.
  12. Karlin, N. J., Weintraub, N., & Chopra, I. J., "Current controversies in endocrinology: screening of asymptomatic elderly for subclinical hypothyroidism", Journal of American Medical Directors Association, Vol. 5, No. 5, pp. 333-336, 2004.
  13. Roberts, K. J., Lepore, S. J., & Urken, M. L., "Quality of life after thyroid cancer: an assessment of patient needs and preferences for information and support", Journal of Cancer Education, Vol. 23, No. 3, pp. 186-191, 2008.
  14. Sonino, N., Tomba, E., & Fava, G. A., "Psychosocial approach to endocrine disease", Advances in Psychosomatic Medicine, Vol. 28, pp. 21-33, 2007.
  15. Tagay, S., Herpertz, S., Langkafel, M., Erim, Y., Freudenberg, L., Schopper, N., Bockisch, A., Senf, W., & Gorges, R., "Health-related quality of life, anxiety and depression in thyroid cancer patients under short-term hypothyroidism and TSH-suppressive levothyroxine treatment", European Journal of Endocrinology, Vol. 153, No. 6, pp. 755-763, 2005.
  16. Huang, S. M., Lee, C. H., Chien, L. Y., Liu, H. E., & Tai, C. J., "Postoperative quality of life among patients with thyroid cancer", Journal of Advanced Nursing, Vol. 47, No. 5, pp. 492-499, 2004.
  17. 김경원, 이은경, 이은정, 이유진, 최성희, 임수, 장혁재, 박영주, 박도준, 박경수, 장학철, 김성연, 이홍규,조보연, "갑상선암환자의 방사성요오드 치료 시 T4 투여 중단 전후의 갑상선기능변화에 따른 심혈관계지표들의 변화", 2007 대한내분비학회 춘계학술지, p.110, 2007.
  18. 정찬희, 이은정, 조숙경, 원종철, 박철영, 이원영, 오기원, 박성우, 김선우, "정상 갑상선 기능을 보이는 일반 성인에서 갑상선 기능과 대사증후군과의 연관성", 2007 대한내분비학회 춘계학술지, pp. 126, 2007.
  19. 송영기, 김원배, 김태용, "갑상선호르몬과 심혈관 질환", 대한내분비학회지, 제19권, 제6호, pp.606-615, 2004.
  20. 이잔디, 윤지섭, 정종주, 남기현, 정웅윤, 소의영, 박정수, "여포상 갑상선암: 임상병리적 특징, 예후인자및 치료전략", 대한외과학회지, 제74권, 제1호, pp. 34-41, 2008.
  21. 국립암센터 갑상선암클리닉, "갑상선암 100문 100답", 국립암센터, pp. 34-37, 2009.
  22. Innes, S. & Payne, S., "Advanced cancer patients' prognostic information preferences: a review", Palliative Medicine, Vol. 23, pp. 29-39, 2009.
  23. Stajduhar, K. I., Neithercut, J., Chu, E., Pham, P., Rohd,e J., Sicotte, A., Young, K., "Thyroid cancer: patients' experiences of receiving iodine-131 therapy", Oncology Nursing Forum, Vol. 27, No. 8, pp. 1213-1218, 2000.
  24. Fitch M. I., & McGrath, P. N., "The needs of family members of patients receiving radioactive iodine", Canadian Oncology Nursing Journal, Vol. 13, No. 4, pp. 220-231, 2003.
  25. Sawka, A. M., Goldstein, D. P., Brierley, J. D., Tsang, R. W., Rotstein, L., Ezzat, S., Straus, S., George, S. R., Abbey, S., Rodin, G., O'Brien, M. A., Gafni, A., Thabane, L., Goguen, J., Naeem, A., & Magalhaes, L., "The impact of thyroid cancer and post-surgical radioactive iodine treatment on the lives of thyroid cancer survivors: A qualitative study", PLoS ONE, Vol. 4, No 1, e4191.doi:10.1371/journal.pone.0004191.
  26. 송창면, 김희진, 권택균, 성명훈, 김광현, 하정훈, "갑상선 수술 환자의 입원 만족도를 높이기 위한 환자의 질병에 대한 이해도, 관심 사항 및 회복도 조사", Korean Journal of Otorhinolaryngology-Head Neck Surgery, 제53권, pp.557-563, 2010
  27. Schultz, P. N., "Providing information to patients with a rare cancer: using Internet discussion forums to address the needs of patients with medullary thyroid carcinoma", Clinical Journal of Oncology Nursing, Vol. 6, No. 4, pp. 219-22, 2002.
  28. 노지호, 김병일, 하지수, 장세중, 신혜영, 최준혁, 김도민, 김종순, "갑상선암의 방사성요오드치료를 위한 저요오드식이 방법 차이에 따른 소변 중요오드/크레아티닌 비의 비교", 핵의학분자영상, 제40권, 제6호, pp. 322-326, 2006.
  29. Thorne, S. E., Bultz, B. D., Baile, W. F., & The SCRN Communication Team., "Is there a cost to poor communication in cancer care?:a critical review of the literature", Psycho-Oncology, Vol. 14, pp. 875-884, 2005.