Functional Cosmetic Effect of Porcine Placeta

Porcine Placenta의 기능성 화장품소재 특성

  • Kim, Bo Young (Amaranth Cosmetics) ;
  • Kim, Tagon (Department of Pharmaceutical Engineering, Inje University) ;
  • Kang, Whan Yul (Amaranth Cosmetics) ;
  • Baek, Hyun (Amaranth Cosmetics) ;
  • Cheon, Hae Young (Amaranth Cosmetics) ;
  • Kim, Donguk (Department of Pharmaceutical Engineering, Inje University)
  • 김보영 (아마란스화장품) ;
  • 김타곤 (인제대학교 제약공학과) ;
  • 강환열 (아마란스화장품) ;
  • 백현 (아마란스화장품) ;
  • 전혜영 (아마란스화장품) ;
  • 김동욱 (인제대학교 제약공학과)
  • Received : 2010.02.17
  • Accepted : 2010.03.10
  • Published : 2010.06.30

Abstract

Porcine placenta was treated with alkali, acid and enzyme treatment to obtain extracts. Heavy metal contents such as Pb, As, and Hg were low enough to satisfy cosmetic agent standard. As a result of safety test(MTT assay), porcine placenta extracts showed over 80% of cell viability at $50{\mu}g/ml$, and cell toxicity was relatively lower. From antioxidation test using DPPH free radical scavenging assay, antioxidation effect was highest as 63% at $50{\mu}g/ml$ when porcine placenta was treated with alkali in pH 9. From whitening effect test using tyrosinase inhibition assay, tyrosinase inhibition effect was 30% at $50{\mu}g/ml$ concentration in alkali treated procine placenta, however, the efficiency was lower compared with arbutin or vitamin C. In anti-wrinkle effect test from elastase inhibition assay, elastase inhibition effects were 20~30% at $50{\mu}g/ml$ for 5 kinds of porcine placenta treatments, which was superior to standard, and especially, protease treated extracts showed best results. Skin formulation including 1% porcine placenta was made and the formulation was very stable for temperature and storage period. From this research, porcine placenta extract showed high potential for anti-wrinkle functional cosmetic agent.

Keywords

Porcine Placenta;Extraction;Whitening;Anti-wrinkle;Stability Test

Acknowledgement

Supported by : 한국산업기술진흥원

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