DOI QR코드

DOI QR Code

Inhibitory effects on colonization of Streptococcus mutans by eighteen months xylitol consumption

18개월간 자일리톨 껌 저작에 따른 Streptococcus mutans의 집락 형성 억제효과

  • Park, Ji-Hye (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University) ;
  • Ahn, Sang-Hun (Dept of Medical Dentistry, College of Medicine, Dongguk University) ;
  • Gu, Hyo-Jin (Dept. of Dental Hygiene, College of Health Sciences) ;
  • Choi, Youn-Hee (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University) ;
  • Song, Keun-Bae (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University)
  • 박지혜 (경북대학교 치과대학 예방치과학교실) ;
  • 안상헌 (동국대학 의과대학 치과학교실) ;
  • 구효진 (춘해보건대학 치위생과) ;
  • 최연희 (경북대학교 치과대학 예방치과학교실) ;
  • 송근배 (경북대학교 치과대학 예방치과학교실)
  • Published : 2010.01.31

Abstract

The purpose of this study was to evaluate suppression of Streptococcus mutans(S. mutans) colonization by long-term xylitol consumption among pregnant women who can easily get bad oral hygiene status during pregnancy and breast feeding. Participants were voluntarily recruited for a pregnant women's oral health prevention program, classified into two groups(a control and a xylitol group), and then followed for 18 months. Stimulated whole saliva was collected in the afternoon(1:00-3:00 p.m.) at baseline, 6 months, 12months, and 18 months. Information regarding oral health behavior(tooth brushing frequency and regular dental visits) was obtained via a questionnaire. S. mutans counts of the xylitol group decreased considerably between baseline and the re-examinations at 6, 12, and 18 months. Although the S. mutans counts decreased for all time points compared to baseline in the control group, these differences did not reach significance except 18 months. Regular chewing of xylitol gum over a long period may lead to decrease the colony counts of S. mutans.

Keywords

Inhibitory effects;S. mutans colonization;xylitol consumption

References

  1. Touger-Decker R, van Loveren C, "Sugars and dental caries", Am J Clin Nutr, 제74권, 제4호, pp. 881S-892S, 10월, 2003.
  2. Makinen KK, Bennett CA, Hujoel PP, Isokangas PJ, Isotupa KP, Pape HR, Makinen PL, "Xylitol chewing gums and caries rates: a 40-month cohort study", J Dent Res, 제74권, 제12호, pp. 1904-1913, 12월, 1995. https://doi.org/10.1177/00220345950740121501
  3. Haresaku S, Hanilka T, Tsutsui A, Yamamoto M, Chou T, Gunjishima Y, "Long-term effect of xylitol gum use on mutans Streptococci in adults", Caries Res, 제41권, 제3호, pp. 198-203, 4월, 2007. https://doi.org/10.1159/000099318
  4. Scheinin A, Makinen KK, Ylitalo K, "Turku sugar studies. V. Final report on the effect of sucrose, fructose and xylitol diets on the caries incidence in man", Acta Odontol Scand, 제34권, 제4호, pp. 179-216, 8월, 1976. https://doi.org/10.3109/00016357608997711
  5. Giertsen E, Emberland H, Scheie AA, "Effects of mouth rinses with xylitol and fluoride on dental plaque and saliva", Caries Res, 제33권, 제1호, pp. 23-31, 1월, 1999. https://doi.org/10.1159/000016492
  6. Hildebrandt GH, Sparks BS, "Maintaining mutans streptococci suppression with xylitol chewing gum", J Am Dent Assoc, 제131권, 제7호, pp. 909-916, 7월, 2000. https://doi.org/10.14219/jada.archive.2000.0309
  7. Isokangas P, Alanen P, Tiekso J, Makinen KK, "Xylitol chewing gum in caries prevention: a field study in children", J Am Dent Assoc, 제117권, 제2 호, pp. 315-320, 8월 1988. https://doi.org/10.1016/S0002-8177(88)72017-6
  8. Petersen PE, Razanamihaja N, "Carbamide - containing polyol chewing gum and prevention of dental caries in school children in Madagascar", Int Dent J, 제49권, 제4호, pp. 226-230, 8월 1999. https://doi.org/10.1111/j.1875-595X.1999.tb00526.x
  9. Alanen P, Isokangas P, Gutman K, "Xylitol candies in caries prevention: results of a field study in Estonian children", Community Dent Oral Epidemiol, 제28권, 제3호, pp. 218-224, 6월, 2000. https://doi.org/10.1034/j.1600-0528.2000.280308.x
  10. Machiulskiene V, Nyvad B, Baelum V, "Caries preventive effect of sugar substituted chewing gum", Community Dent Oral Epidemiol, 제29권, 제4호, pp. 278-288, 8월, 2001. https://doi.org/10.1034/j.1600-0528.2001.290407.x
  11. Stecksen-Blicks C, Holgerson PL, Olsson M, Bylund B, Sjostrom I, Skold-Larsson K, Kalfas S, Twetman S, "Effect of xylitol on mutans streptococci and lactic acid formation in saliva and plaque from adolescents and young adults with fixed orthodontic appliances", .Eur J Oral Sci, 제112권, 제3호, pp. 244-248, 6월, 2004. https://doi.org/10.1111/j.1600-0722.2004.00130.x
  12. Milgrom P, Ly KA, Robert MC, Rothen M, Mueller G, Yamaguchi DK, "Mutans Streptococci dose response to xylitol chewing gum", J Dent Res, 제85 권, 제2호, pp. 177-181, 2월, 2006. https://doi.org/10.1177/154405910608500212
  13. Holgerson PL, Sjostrom I, Stecksen-Blicks C, Twetman S, "Dental plaque formation and salivary mutans streptococci in schoolchildren after use of xylitol-containing chewing gum", Int J Paediatr Dent, 제17권, 제2호, pp. 79-85, 2007;17(2):79-85. https://doi.org/10.1111/j.1365-263X.2006.00808.x
  14. Caglar E, Kavaloglu SC, Kuscu OO, Sandalli N, Holgerson PL, Twetman S, "Effect of chewing gums containing xylitol or probiotic bacteria on salivary mutans streptococci and lactobacilli", Clin Oral Investig, 제11권, 제4호, pp. 425-429, 12월, 2007. https://doi.org/10.1007/s00784-007-0129-9
  15. Makinen KK, Isotupa KP, Makinen PL, Soderling E, Song KB, Nam SH, Jeong SH, "Six-month polyol chewing-gum programme in kindergarten-age children: a feasibility study focusing on mutans streptococci and dental plaque", Int Dent J, 제55권, 제2호, pp. 81-88, 4월, 2005. https://doi.org/10.1111/j.1875-595X.2005.tb00038.x
  16. 박재홍, "혼합치열기 어린이에서 mutans streptococci에 대한 자일리톨 껌의 항균효과에 관한 연구", 대한소아치과학회지, 제34권, 제4호, pp. 632-638, 12월, 2007.
  17. Soderling E, Isokangas P, Tenovuo J, Mustakallio S, Mäkinen KK, "Long-term xylitol consumption and mutans streptococci in plaque and saliva", Caries Res, 제25권, 제2호, pp. 153-157, 4월, 1991. https://doi.org/10.1159/000261359
  18. Trahan L, "Xylitol: a review of its action on mutans streptococci and dental plaque-its clinical significance", Int Dent J, 제45권, 제1호, pp. 77-92, 2월 1995.
  19. Trahan L, Soderling E, Drean MF, Chevrier MC, Isokangas P, "Effect of xylitol consumption on the plaque-saliva distribution of mutans streptococci and the occurrence and long-term survival of xylitol-resistant strains", J Dent Res, 제71권, 제11호, pp. 1785-1791, 11월, 1992. https://doi.org/10.1177/00220345920710110401
  20. Trahan L, Mouton C, "Selection for Streptococcus mutans with an altered xylitol transport capacity in chronic xylitol consumers", J Dent Res, 제66권, 제5호, pp. 982-988, 5월, 1987. https://doi.org/10.1177/00220345870660052301
  21. Lee YE, Choi YH, Jeong SH, Kim HS, Lee SH, Song KB, "Morphological changes in Streptococcus mutans after chewing gum containing xylitol for twelve months", Curr Microbiol, 제58권, 제4호, pp. 332-337, 4월 2009. https://doi.org/10.1007/s00284-008-9332-4