Inhibitory effects on colonization of Streptococcus mutans by eighteen months xylitol consumption

18개월간 자일리톨 껌 저작에 따른 Streptococcus mutans의 집락 형성 억제효과

  • Park, Ji-Hye (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University) ;
  • Ahn, Sang-Hun (Dept of Medical Dentistry, College of Medicine, Dongguk University) ;
  • Gu, Hyo-Jin (Dept. of Dental Hygiene, College of Health Sciences) ;
  • Choi, Youn-Hee (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University) ;
  • Song, Keun-Bae (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University)
  • 박지혜 (경북대학교 치과대학 예방치과학교실) ;
  • 안상헌 (동국대학 의과대학 치과학교실) ;
  • 구효진 (춘해보건대학 치위생과) ;
  • 최연희 (경북대학교 치과대학 예방치과학교실) ;
  • 송근배 (경북대학교 치과대학 예방치과학교실)
  • Published : 2010.01.31


The purpose of this study was to evaluate suppression of Streptococcus mutans(S. mutans) colonization by long-term xylitol consumption among pregnant women who can easily get bad oral hygiene status during pregnancy and breast feeding. Participants were voluntarily recruited for a pregnant women's oral health prevention program, classified into two groups(a control and a xylitol group), and then followed for 18 months. Stimulated whole saliva was collected in the afternoon(1:00-3:00 p.m.) at baseline, 6 months, 12months, and 18 months. Information regarding oral health behavior(tooth brushing frequency and regular dental visits) was obtained via a questionnaire. S. mutans counts of the xylitol group decreased considerably between baseline and the re-examinations at 6, 12, and 18 months. Although the S. mutans counts decreased for all time points compared to baseline in the control group, these differences did not reach significance except 18 months. Regular chewing of xylitol gum over a long period may lead to decrease the colony counts of S. mutans.


Inhibitory effects;S. mutans colonization;xylitol consumption


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