Status and Future Prospects of Pest Control Agents in Environmentally-friendly Agriculture, and Importance of their Commercialization

친환경농업 해충방제용 제제의 현황과 전망, 그리고 산업화의 중요성

  • Kim, In-Seon (Division of Applied Bioscience and Biotechnology, College of Agriculture and Life Sciences, Chonnam National University) ;
  • Kim, Ik-Soo (Division of Plant Biotechnology, College of Agriculture and Life Sciences, Chonnam National University)
  • 김인선 (전남대학교 농업생명과학대학 응용생물공학부) ;
  • 김익수 (전남대학교 농업생명과학대학 식물생명공학부)
  • Published : 2009.09.30


The use of bioactive materials derived from microorganisms and plants has played a role in pest management in environmentally-friendly agriculture (EFA) system. In Korea, a number of agricultural agents for the control of insect pests have been registered officially as biopesticides and marketed widely. However, most of the biopesticides has a limitation in the resource availability of bioactive materials, which has been one of main problems related to the commercialization of agricultural agents. Plant materials and microbial metabolites are the best sources as starting components to commercialize natural-occurring agricultural agents for pest management. The lack of modernized system for the standardization and quality control of the starting materials, however, has also received as a main problem related to the commercialization of agricultural agents. Considered that EFA business has kept growing bigger and bigger with global economic status, the commercialization of agricultural agents is necessary to meet the required number of agricultural agents officially available in EFA. This study describes the status and future prospects of pest control agents in EFA. A number of main issues hindered in the commercialization of agricultural agents are discussed in order to present a promising approach to successful commercialization.


  1. Copping, L. G. and Duke, S. O. (2007) Natural products that have been used commercially as crop protection agents, Pest Manag. Sci. 63, 524-554
  2. Edelson, J. V., Duthie, J., and Roberts, W. (2002) Toxicity of biorational insecticides: activity against the green peach aphid, Myzus persicase (Sulzer), Pest Manag. Sci. 58, 255-260
  3. Immaraju, J. A. (1998) The commercial use of azadirachtin and its integration into viable pest control programmes, Pest Manag. Sci. 54, 285-280<285::AID-PS802>3.0.CO;2-E
  4. Casanova, H., Ortiz, C., Peleáz, C., Valleio, A., and Moreno, M. E. (2002) Insecticide formulations based on nicotine oleate stabilized by sodium caseinate, J. Agric. Food Chem. 50, 6389-6394
  5. Crombie, L. (1999) Natural product chemistry and its part in the defence against insects and fungi in agriculture, Pestic. Sci. 55, 761-774<761::AID-PS26>3.0.CO;2-2
  6. Michereff-Filho, M., Torres, J. B., Andrade, L. NT, and Nunes, M. U. C (2008) Effect of some biorational insecticides on spodoptera eridania in organic cabbage, Pest Manag. Sci. 64, 761-767
  7. Schnepf, E., Crockmore, N., Van Rie, J., Lereclus, D., Baum, J., Feitelson, J., Zeigler, D. R., and Dean, D. H. (1998) Bacillus thuringiensis and its pesticidal crystal proteins, Microbiol. Mol. Biol. Rev. 62, 775-806
  8. Lee, S. G., Choi, K. H., Lee, Y. S., Oh, K. S., O, J. H., and Choi, S. W. (2006) Insecticidal activities against major lepidopteran pests and culture condition of Bacillus thuringiensis sp. aizawa collected in Korea, Kor. J. Pesti. Sci. 10, 131-137
  9. Roh, J. Y., Choi, J. Y., Li, M. S., Jin, B. R., and Je, Y. H. (2007) Bacillus thuringiensis as a specific, safe, and effective tool for insect pest control, J. Microbiol. Biotechnol. 17, 547-559
  10. Bravo, A., Gill, S. S., and Soberỏn, M. (2007) Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control, Toxicon. 49, 423-435
  11. Mordue (Luntz) A. J., Simmonds, M. S. J., Ley, S. V., Blaney, W. M., Mordue, W., Nasiruddin, M., and Nisbet, A. J. (1998) Actions of azadirachtin, a plant allelochemical, against insects, Pestic. Sci. 54, 277-284<277::AID-PS801>3.0.CO;2-I
  12. Kraiss, H. and Cullen, E. M. (2008) Insect growth regulator effects of azadirachtin and neem oil on survivorship, development and fecundity of Aphis glycines (Homoptera: Aphididae) and its predator, Harmonia axyridis (Coleoptera: Coccinellidae), Pest Manag. Sci. 64, 660-668
  13. Isman, M. B. (2001) Biopesticides based on phytochemicals, p. 1-12, In Koul, O. and Dhaliwal, G. S. (ed.), Phytochemical biopesticides, Harwood Academic Press, Amsterdam, The Netherland
  14. Rich, R. P. (1996) Quinone binding sites of membrane proteins as targets for inhibitors, Pestic. Sci. 47, 287-296<287::AID-PS405>3.0.CO;2-B
  15. Caboni, P., Sherer, T. B., Zhang, N., Taylor, G., Na, H. M., Greenamyre, J. T., and Casida, J. E. (2004) Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease, Chem. Res. Toxicol. 17, 1540-1548
  16. Katsuda, Y. (1999) Development of and future prospects for pyrethroid chemistry, Pestic. Sci. 55, 775-782<775::AID-PS27>3.0.CO;2-N
  17. Soderlund, D. M. (2008) Pyrethroids, knockdown resistance and sodium channels, Pest Manag Sci. 64, 610-616
  18. Millar, N. S. and Denholm, I. (2007) Nicotinic acetylcholine receptors: targets for commercially important insecticides, Invert. Neurosci. 7, 53-65
  19. Isman, M. B. (2006) Botanical insecticides, deterrents, and repellents in modern agriculture and increazsing regulated world, Annu. Rev. Entomol. 51, 45-66

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