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Clinical Characteristics and Prognosis of Lung Cancer Patients Admitted to the Medical Intensive Care Unit at a University Hospital

한 대학병원 내과계 중환자실로 입원한 폐암 환자들의 임상 특성 및 예후

  • Moon, Kyoung Min (Department of Internal Medicine, Eulji University School of Medicine) ;
  • Han, Min Soo (Department of Internal Medicine, Eulji University School of Medicine) ;
  • Lee, Sung Kyu (Department of Internal Medicine, Eulji University School of Medicine) ;
  • Jeon, Ho Seok (Department of Internal Medicine, Eulji University School of Medicine) ;
  • Lee, Yang Deok (Department of Internal Medicine, Eulji University School of Medicine) ;
  • Cho, Yong Seon (Department of Internal Medicine, Eulji University School of Medicine) ;
  • Na, Dong Jib (Department of Internal Medicine, Eulji University School of Medicine)
  • 문경민 (을지대학교 의과대학 내과학교실) ;
  • 한민수 (을지대학교 의과대학 내과학교실) ;
  • 이성규 (을지대학교 의과대학 내과학교실) ;
  • 전호석 (을지대학교 의과대학 내과학교실) ;
  • 이양덕 (을지대학교 의과대학 내과학교실) ;
  • 조용선 (을지대학교 의과대학 내과학교실) ;
  • 나동집 (을지대학교 의과대학 내과학교실)
  • Received : 2008.11.06
  • Accepted : 2008.12.12
  • Published : 2009.01.30

Abstract

Background: The management of patients with lung cancer has improved recently, and many of them will require admission to the medical intensive care unit (MICU). The aim of this study was to examine the clinical characteristics and to identify risk factors for mortality in patients with lung cancer admitted to the MICU. Methods: We conducted retrospective analysis on 88 patients with lung cancer admitted to the MICU between April 2004 and March 2008. Results: Of the 88 patients (mean age, 66 years), 71 patients (80.7%) had non-small cell lung cancer and 17 patients (19.3%) had small cell lung cancer. Distant metastasis were present in 79 patients (89.8%). The main reasons for MICU admission were acute respiratory failure (77.3%), sepsis (11.4%), and central nervous system dysfunction (4.5%). Mechanical ventilation was used in 54 patients (61.4%). Acute Physiology and Chronic Health Evaluation (APACHE) II score, length of MICU stay, need for mechanical ventilation, source of MICU admission were correlated with MICU mortality. The type of lung cancer and metastasis were not predictive factors of death in MICU. Conclusion: Most common reason for ICU admission was acute respiratory failure. Mortality rate of lung cancer patients admitted to the MICU was 65.9%. APACHE II score, length of ICU stay, need for mechanical ventilation, source of MICU admission were predicted factors of death in the MICU.

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