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A Study on the Efficacy of Dietary Supplementation of Organic Acid Mixture in Broiler Chicks

육계에 대한 복합 유기산제의 첨가급여 효과에 관한 연구

  • Kim, Dong-Wook (National Institute of Animal Science, R.D.A.) ;
  • Kim, Ji-Hyuk (National Institute of Animal Science, R.D.A.) ;
  • Kim, Sung-Kwon (College of Animal Bioscience & Technology, Konkuk University) ;
  • Kang, Geun-Ho (National Institute of Animal Science, R.D.A.) ;
  • Kang, Hwan-Ku (National Institute of Animal Science, R.D.A.) ;
  • Lee, Sang-Jin (National Institute of Animal Science, R.D.A.) ;
  • Kim, Sang-Ho (National Institute of Animal Science, R.D.A.)
  • 김동욱 (농촌진흥청 국립축산과학원) ;
  • 김지혁 (농촌진흥청 국립축산과학원) ;
  • 김성권 (건국대학교 동물생명과학대학) ;
  • 강근호 (농촌진흥청 국립축산과학원) ;
  • 강환구 (농촌진흥청 국립축산과학원) ;
  • 이상진 (농촌진흥청 국립축산과학원) ;
  • 김상호 (농촌진흥청 국립축산과학원)
  • Received : 2009.01.08
  • Accepted : 2009.05.08
  • Published : 2009.06.01

Abstract

This experiment was conducted to investigate the effects of dietary supplementation of organic acid mixture on growth performance, cecal microflora, blood characteristics and immune response in broiler chicks and to prove the possibility of organic acid mixture as an alternative to antibiotics growth promotor. A total of four hundred eighty, 1-day-old male broiler chicks (Ross$\times$Ross 308) were randomly divided into 4 groups with 4 replicates of 30 birds each. The treatments were NC (free antibiotics), PC (basal diet with virginiamycin 10 ppm and salinomycin 60 ppm), 0.3% organic acid, and 0.5% organic acid. The final body weight and body weight gain were significantly higher in organic acid 0.5% than NC (P<0.05). The feed conversion ratio in all treated groups were significantly improved as compared to that of NC (P<0.05). The carcass rate and relative organs weight were not significantly difference among the groups. The relative weight and length of small intestine in PC were significantly decreased than the other groups. The numbers of cecal coliform bacteria and Salmonella in all treated groups were significantly lower than NC (P<0.05). The number of cecal lactic acid bacteria was not different among the groups. No significant differences among the groups were observed in the contents of total cholesterol, triglyceride, blood urea nitrogen (BUN), albumin, aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in blood serum. The contents of total protein and globulin in blood serum of PC and organic acid treated groups were significantly increased as compared to those of NC (P<0.05). Therefore, albumin:globulin ratio of PC and organic acid treated groups was significantly lower than NC (P<0.05). The total white blood cell (WBC), heterophil, lymphocyte, and stress indicator (heterophil:lymphocyte ratio) were not significantly different among the groups. No significant difference was observed on the expression rate of splenic cytokines mRNA in organic acid treated groups compared to the control. Consequently, supplemental organic acid mixture improved the growth performance, and influenced positive effects on the intestinal microflora by inhibiting the growth of harmful bacteria without any adverse effects on relative weights of organs and blood biochemical parameters in broiler chicks.

Keywords

Organic acid;Broiler;Growth performance;Cecal microflora;Blood biochemical parameter;Cytokine

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