Commercial Application of Porcine MC1R Gene Polymorphisms to Korean Pork Industry

돼지 MC1R 유전자변이의 양돈산업 적용

  • Ha, You-Kyoung (Department of Animal Science, Chungbuk National University) ;
  • Choi, Jung-Suk (Department of Animal Science, Chungbuk National University) ;
  • Kim, Sang-Wook (Department of Animal Science, Chungbuk National University) ;
  • Choi, Yang-Il (Department of Animal Science, Chungbuk National University) ;
  • Lee, Seug-Soo (National Livestock Research Institute) ;
  • Choi, Jae-Won (ChungBuk Institute of Livestock and Veterinary Research) ;
  • Jeon, Soon-Hong (ChungBuk Institute of Livestock and Veterinary Research) ;
  • Kim, Kwan-Suk (Department of Animal Science, Chungbuk National University)
  • 하유경 (충북대학교 농업생명환경대학 축산학과) ;
  • 최정석 (충북대학교 농업생명환경대학 축산학과) ;
  • 김상욱 (충북대학교 농업생명환경대학 축산학과) ;
  • 최양일 (충북대학교 농업생명환경대학 축산학과) ;
  • 이승수 (국립축산과학원 개량평과과) ;
  • 최재원 (충청북도 축산위생연구소) ;
  • 전순홍 (충청북도 축산위생연구소) ;
  • 김관석 (충북대학교 농업생명환경대학 축산학과)
  • Received : 2009.05.08
  • Accepted : 2009.06.09
  • Published : 2009.06.01


The pork from black-coated pigs is famous among-consumers for better eating quality. The loci affecting black coat color was identified in pig chromosome 6 in which several genetic effects on pork quality have been reported. The melanocortin 1 receptor (MC1R) gene is a major gene which plays a key role in regulation of eumelanin (black/brown) and phaeomelanin (red/yellow). In this study, the MC1R gene polymorphism was analyzed for pig breed determination and genetic association with pork quality traits. MC1R Ala243Thr variation was analyzed to determine a specific genotype for four commercial pig breeds (Landrace, Yorkshire, Berkshire and, Duroc) and a Korean native pigs (KNP). Then we developed original KNP-specific DNA markers to determine the pork from black-coated pigs using MC1R DNA sequences. The total length of the MC1R coding sequence ranged 1451bp in KNP. KNP had the 0201 allele pertaining to $E^{D1}$ but some of the KNP had the $E^P$ allele, probably reflecting the geneticintrogression of $E^P$ allele into KNP. Furthermore, a relationship between Leu102Pro single nucleotide polymorphism (SNP) genotype and pork quality phenotype were analyzed in F2 reciprocal-crossbred population between KNP and Yorkshire. Association analysis indicated that the allele of the MC1R gene has no effect on pork quality. These results suggest that black coat-color is not directly associated with preferred pork quality, but the black-coat color pig breed may have other genetic components for superior pork quality.


MC1R;KNP;Polymorphism;Pork quality


Grant : DNA 마커 도움선발을 이용한 한국재래돼지 개량과 상업적 비육흑돼지 계통조성

Supported by : 충북대학교


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