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Effects of Dietary Garlic Powder on Growth Performance and mRNA Expression of Hepatic HMG-CoA Reductase in Broiler Chickens

육계 사료 내 마늘분말의 첨가급여가 육계 성장과 HMG-CoA Reductase의 mRNA 발현에 미치는 영향

  • You, Sun-Jong (Animal Resources Research Center, College of Animal Bioscience and Technology, Konkuk University) ;
  • Ahn, Byoung-Ki (Animal Resources Research Center, College of Animal Bioscience and Technology, Konkuk University) ;
  • Kang, Chang-Won (Animal Resources Research Center, College of Animal Bioscience and Technology, Konkuk University)
  • 유선종 (건국대학교 동물생명과학대학 동물자원연구센터) ;
  • 안병기 (건국대학교 동물생명과학대학 동물자원연구센터) ;
  • 강창원 (건국대학교 동물생명과학대학 동물자원연구센터)
  • Received : 2009.02.20
  • Accepted : 2009.07.14
  • Published : 2009.08.01

Abstract

This experiment was conducted to investigate the effects of dietary garlic powder (GP) on growth performance and mRNA expression of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-CoA reductase) in broiler chickens. Day-old male chicks (Ross, n=270) were fed diets containing 0% [positive control (PC) with antibiotics or negative control (NC) without antibiotics], 1%, 3% and 5% GP for 6 wks. There were no significant differences in feed intake among the treatments throughout the experimental period. Body weight gains in groups fed dietary GP at 3% and 5% were significantly higher than that of NC group (P<0.05). Feeding GP up to 5% did not exert any adverse effect on weight gain and feed intake. There were no significant differences in the relative weights of liver, spleen, cecum and breast muscle. The content of meat cholesterol in GP containing dietary groups tended to be reduced as compared to NC group. Average infectious bronchitis antibody titers in chicks fed GP containing diets were significantly higher than that of NC group (P<0.05). The mRNA expression of hepatic HMG-CoA reductase was reduced by dietary GP. These results indicate that dietary GP has growth promoting effects and tended to alter cholesterol metabolism in broiler chickens.

Keywords

Garlic;HMG-CoA reductase;Growth performance;Broiler chicken

Acknowledgement

Supported by : 농림수산식품부

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