Antibacterial Activity of Platycarya strobilacea Extract and Stability of the Extract-containing Cream

굴피나무 추출물의 항균 활성 및 추출물을 함유한 크림의 안정성 분석

  • Yang, Hee-Jung (Department of Fine Chemistry, College of Nature & Life Science, Seoul National University of Technology) ;
  • Kim, Eun-Hee (Department of Fine Chemistry, College of Nature & Life Science, Seoul National University of Technology) ;
  • Kang, Sung-Tae (Department of Food Science and Technology, College of Nature & Life Science, Seoul National University of Technology) ;
  • Park, Soo-Nam (Department of Fine Chemistry, College of Nature & Life Science, Seoul National University of Technology)
  • 양희정 (서울산업대학교 자연생명과학대학 정밀화학과) ;
  • 김은희 (서울산업대학교 자연생명과학대학 정밀화학과) ;
  • 강성태 (서울산업대학교 자연생명과학대학 식품공학과) ;
  • 박수남 (서울산업대학교 자연생명과학대학 정밀화학과)
  • Received : 2009.03.06
  • Accepted : 2009.04.13
  • Published : 2009.06.28

Abstract

The extract of Platycarya strobilacea is known to possess a wide range of pharmacological activities including anti-inflammatory, anti-fungal, and anti-cancer properties. We have reported that the ethyl acetate fraction of Platycarya strobilacea (PS-ET fraction) has high potential as an antioxidant agent (J. Soc. Cosmet. Scientists Korea 34(4) 275, 2008). In this study, antibacterial activity of the fraction and stability of the cream containing 0.2% PS-ET fraction were investigated for the application to cosmetics. Antibacterial activity of PS-ET fraction against various skin pathogenic bacteria (Propionibacterium acnes, Staphylococcus aureus, and Pityrosporum ovale) was measured by minimum inhibitory concentration (MIC). MIC values of PS-ET fraction on P. acnes, S. aureus, and P. ovale were 0.13%, 0.06% and 0.25%, respectively. The results showed that the antibacterial activity of the fraction was the highest in the S. aureus. For the stability evaluation, pH and viscosity of the cream containing 0.2% PS-ET fraction were measured. The results showed that pH changes of the cream containing PS-ET fraction was lower than the control cream without PS-ET fraction. And the PS-ET fraction could repress the decrease of viscosity of the cream against sunlight treatment. These results suggest that the fraction of Platycarya strobilacea has high potential as bactericide against the skin pathogenic bacteria and could be added to improve the stability of cosmetic products.

Keywords

Platycarya strobilacea;antibacterial activity;stability test;cosmetics

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