Overview for pattern and results of moxibustion-derived clinical trials

뜸을 이용한 RCT임상연구의 경향에 대한 개괄

  • Son, Chang-Gue (Liver-Immunity Department of Oriental Medicine College, Daejeon University)
  • 손창규 (대전대학교 한의과대학 간장면역학교실)
  • Published : 2009.03.27


Objective : To make comprehensive picture of clinical trials using moxibustion and their results by today, then help a strategy for moxibustion-derived clinical studies in the future. Methods : Surveyed literatures containing randomized controled clinical trial (RCT) from PubMed and Korean journals. Analysis was performed according to distribution mainly by study subject, target diseases, study design, and its efficacy. Results : Fifty two literatures were selected according to inclusion criteria of randomized controled clinical study. Moxibustion-derived RCT have been rapidly increased from 2003 since the first was published in China in 1992. The main subjects of RCT are associated with immunity, cancer, arthritis, chronic colitis and urogenital disorders, which are connected to cold-elated pathogenesis. The average number of subjects was 94, and direct-moxibustion was mainly applied. The control groups were set up by giving conventional therapy, herbal medicine, acupuncture or only observation. The most of RCTs showed positive results. Conclusions : This study would be helpful for designing or conducting RCTs to develop the scientific development of moxibustion.


  1. 박혜정, 손창규. 국내외의 뜸 연구의 경향에 대한 연구. 경락경혈학회지. 2008 ; 25(3) : 167-74.
  2. 이건목, 이길숭, 이승훈, 장종덕, 서은미, 최정선 등. 뜸의 대중화 및 유용성 방안에 대한 연구. 대한침구학회지. 2003 ; 20 : 63-79
  3. 국민건강보험공단. 2007 건강보험 통계연보. 2008 : 296.
  4. 한창현, 신미숙, 신선화, 강경원, 박선희, 최선미. 국내 뜸 요법 임상 실태 파악을 위한 전화조사. 경락경혈학회지. 2007 ; 24(3) : 17-31.
  5. 한창현, 신미숙, 강경원, 강병갑, 박선희, 최선미. 국내 뜸 요법 임상 실태 파악을 위한 면접조사. 경락경혈학회지. 2008 ; 25(1) : 85-97.
  6. 우현수, 이윤호, 김창환. 구법에 대한 문헌적 고찰 및 최근 연구 경향. 대한침구학회지. 2002 ; 19(4) : 1-15.
  7. Tinsley JA. The hazards of psychotropic herbs. Minn Med. 1999 ; 82(5) : 29-31.
  8. Ghosh AK. Clinical applications and update on evidence-based medicine. J Assoc Physicians India. 2007 ; 55 : 787-94.
  9. Siow YL, Gong Y, Au-Yeung KK, Woo CW, Choy PC et al. Emerging issues in traditional Chinese medicine. Can J Physiol Pharmacol. 2005 ; 83(4) : 321-34. https://doi.org/10.1139/y05-029
  10. Zhou WY, Zhao JG, Han YY, Hong Z, Gao Y. Clinical study of acupuncture and moxibustion for preventing nosocomial infection in the patient with acute cerebrovascular disease. Zhongguo Zhen Jiu. 2008 ; 28(2) : 91-4.
  11. Zhao XX, Lu M, Zhu X, Gao P, Li YL, Wang XM et al. Multi-central clinical evaluation of ginger-partitioned moxibustion for treatment of leukopenia induced by chemotherapy. Zhongguo Zhen Jiu. 2007 ; 27(10) : 715-20.
  12. Liu J, Yu RC, Rao XQ. Study on effect of moxibustion and guben yiliu III combined with chemotherapy in treating middle-late stage malignant tumor. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2001 ; 21(4) : 262-4.
  13. Xie XX, Lei QH. Observation on therapeutic effect of the spreading moxibustion on rheumatoid arthritis. Zhongguo Zhen Jiu. 2008 ; 28(10) :730-2.
  14. Sun K, Yang J, Shen DK. Clinical observation on treatment of primary knee osteoarthritis of liver and kidney deficiency type with Aconite cake-separated moxibustion. Zhongguo Zhen Jiu. 2008 ; 28(2) : 87-90.
  15. Park JS, Kwon SJ, Kwon YS. The effects of Dogbi(ST35) & Sulan moxibustion on knee joint pain, range of motion and discomfort during ADL in the aged. Taehan Kanho Hakhoe Chi. 2006 ; 36(1) : 189-96.
  16. Sun H, Wang DH. Clinical observation on different acupuncture and moxibustion therapies for treatment of postsurgical gastroparesis syndrome. Zhongguo Zhen Jiu. 2007 ; 27(3) : 173-5.
  17. Joos S, Wildau N, Kohnen R, Szecsenyi J, Schuppan D, Willich SN et al. Acupuncture and moxibustion in the treatment of ulcerative colitis: a randomized controlled study. Scand J Gastroenterol. 2006 ; 41(9) : 1056-63. https://doi.org/10.1080/00365520600580688
  18. Joos S, Brinkhaus B, Maluche C, Maupai N, Kohnen R, Kraehmer N et al. Acupuncture and moxibustion in the treatment of active Crohn's disease: a randomized controlled study. Digestion. 2004 ; 69(3) : 131-9. https://doi.org/10.1159/000078151
  19. Zhang X. 23 cases of chronic nonspecific ulcerative colitis treated by acupuncture and moxibustion. J Tradit Chin Med. 1998 ; 18(3) : 188-91.
  20. Neri I, De Pace V, Venturini P, Facchinetti F. Effects of three different stimulations (acupuncture, moxibustion, acupuncture plus moxibustion) of BL67 acupoint at small toe on fetal behavior of breech presentation. Am J Chin Med. 2007 ; 35(1) : 27-33. https://doi.org/10.1142/S0192415X0700459X
  21. Cardini F, Lombardo P, Regalia AL, Regaldo G, Zanini A, Negri MG et al. A randomised controlled trial of moxibustion for breech presentation. BJOG. 2005 ; 112(6) : 743-7. https://doi.org/10.1111/j.1471-0528.2005.00634.x
  22. Neri I, Airola G, Contu G, Allais G, Facchinetti F, Benedetto C. Acupuncture plus moxibustion to resolve breech presentation: a randomized controlled study. J Matern Fetal Neonatal Med. 2004 ; 15(4) : 247-52. https://doi.org/10.1080/14767050410001668644
  23. Neri I, Fazzio M, Menghini S, Volpe A, Facchinetti F. Non-stress test changes during acupuncture plus moxibustion on BL67 point in breech presentation. J Soc Gynecol Investig. 2002 ; 9(3) : 158-62. https://doi.org/10.1016/S1071-5576(02)00145-4
  24. Cardini F, Weixin H. Moxibustion for correction of breech presentation: a randomized controlled trial. JAMA. 1998 ; 280(18) : 1580-4. https://doi.org/10.1001/jama.280.18.1580
  25. Yun SP, Jung WS, Park SU, Moon SK, Park JM, Ko CN et al. Effects of moxibustion on the recovery of post-stroke urinary symptoms. Am J Chin Med. 2007 ; 35(6) : 947-54. https://doi.org/10.1142/S0192415X07005417
  26. Liu HL, Wang LP. Randomized controlled study on ginger-saltpartitioned moxibustion at shenque (CV8) on urination disorders poststroke. Zhongguo Zhen Jiu. 2006;26(9):621-4.
  27. Xue YP, Zhang SB, Gao T. Observation on therapeutic effect of chronic prostatitis treated mainly by warming needle moxibustion. Zhongguo Zhen Jiu. 2006 ; 26(5) : 335-6.
  28. Yu Y, Kang J. Clinical studies on treatment of chronic prostatitis with acupuncture and mild moxibustion. J Tradit Chin Med. 2005 ; 25(3) : 177-81.
  29. Sun H, Qiu MY, Li BQ, Wang SH, Chen ZY, Jiang Y et al. Effect of moxibustion on quality of life in hemodialysis patients. Zhongguo Zhen Jiu. 2008 ; 28(5) : 321-4.
  30. Shin KR, Kwak SA, Lee JB, Yi HR. The effectiveness of hand acupuncture and moxibustion in decreasing pain and "coldness" in Korea women who have had hysterectomy: a pilot study. Appl Nurs Res. 2006 ; 19(1) : 22-30. https://doi.org/10.1016/j.apnr.2005.01.003
  31. Lee IS, Choi HS. Effect of Self Moxibustion on Dysmenorrhea and Activities of Daily Living in Female College Students. Korean J Women Health Nurs. 2005 ; 11(1) : 77-82.
  32. Li WL, Liu L, Sun LH. Analysis on therapeutic effect of substancepartitioned moxibustion at Guanyuan (CV 4) and shenque (CV 8) for treatment of primary dysmenorrhea of cold-damp type. Zhongguo Zhen Jiu. 2006 ; 26(7) : 481-2.
  33. Chen RX, Kang MF, He WL, Chen SY, Zhang B. Moxibustion on heat-sensitive acupoints for treatment of myofascial pain syndrome: a multi-central randomized controlled trial. Zhongguo Zhen Jiu. 2008 ; 28(6) : 395-8.
  34. He XW, Wang BY, Huang JH, Zhou SL, Huang XB, Wu JH. Clinical observation on moxibustion and acupuncture at Zusanli (ST36) for treatment of refractory facial paralysis. Zhongguo Zhen Jiu. 2006 ; 26(11) : 775-7.
  35. Li Y, Liang FR, Yu SG, Li CD, Hu LX, Zhou D et al. Efficacy of acupuncture and moxibustion in treating Bell's palsy: a multicenter randomized controlled trial in China. Chin Med J (Engl). 2004 ; 117(10) : 1502-6.
  36. Zhen HL, Wang Y, Liu XJ. Observation on therapeutic effect of warming needle moxibustion on chronic pelvic inflammation of cold-damp stagnation type. Zhongguo Zhen Jiu. 2008 ; 28(10) : 736-8.
  37. Moon SK, Whang YK, Park SU, Ko CN, Kim YS, Bae HS et al. Antispastic effect of electroacupuncture and moxibustion in stroke patients. Am J Chin Med. 2003 ; 31(3) : 467-74 https://doi.org/10.1142/S0192415X03001077
  38. Gentil D, Assumpcao J, Yamamura Y, Barros Neto T. The effect of acupuncture and moxibustion on physical performance by sedentary subjects submitted to ergospirometric test on the treadmill. J Sports Med Phys Fitness. 2005 ; 45(1) : 134-40.
  39. 임종국. 애구의 생체반응에 대한 문헌적 고찰. 동양의학. 1976 ; 2 : 36-40.