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Effects of Dietary Supplementation of Domestic Skullcap (Scutellaria baicalensis) Extracts on Performance, Immune Response and Intestinal Microflora in Broiler Chicken

국내 자생 황금 추출물의 첨가 급여가 육계의 생산성, 면역 기능 및 장내 균총 변화에 미치는 영향

  • Kwon, H.S. (College of Animal Bioscience and Technology, Konkuk University) ;
  • Kim, J.Y. (College of Animal Bioscience and Technology, Konkuk University) ;
  • Kim, J.S. (College of Animal Bioscience and Technology, Konkuk University) ;
  • Lee, B.K. (College of Animal Bioscience and Technology, Konkuk University) ;
  • Lee, S.Y. (College of Animal Bioscience and Technology, Konkuk University) ;
  • Lee, W.S. (College of Animal Bioscience and Technology, Konkuk University) ;
  • Ahn, B.K. (College of Animal Bioscience and Technology, Konkuk University) ;
  • Kim, E.J. (Division of Animal Care, Cheonan Yonam College) ;
  • Kang, C.W. (College of Animal Bioscience and Technology, Konkuk University)
  • 권혁신 (건국대학교 동물생명과학대학) ;
  • 김재영 (건국대학교 동물생명과학대학) ;
  • 김지숙 (건국대학교 동물생명과학대학) ;
  • 이보근 (건국대학교 동물생명과학대학) ;
  • 이소연 (건국대학교 동물생명과학대학) ;
  • 이완섭 (건국대학교 동물생명과학대학) ;
  • 안병기 (건국대학교 동물생명과학대학) ;
  • 김은집 (천안연암대학 동물보호계열) ;
  • 강창원 (건국대학교 동물생명과학대학)
  • Published : 2009.01.02

Abstract

This study was carried out to investigate dietary effects of extracts of Skullcap (Scutellaria baicalensis) (SCE) grown in Korea on growth performance, immune and physiological responses in broiler chickens. Total of seven-hundred fifty 1-d-old Ross male broiler chicks were divided into five groups and fed control diets (antibiotics medicated or non-medicated commercial diets) or each experimental diet (non-medicated diets containing 0.1, 0.3 or 0.5% SCE) for 5 weeks. The body weight gain and feed conversion rate in the groups fed diets containing 0.1% or 0.3% SCE were significantly improved as compared with those of non-medicated control group (P<0.05). The levels of total cholesterol and HDL-cholesterol of blood were not influenced by feeding the SCE. The average antibody titers against NDV and IBV in the groups fed diets containing SCE were significantly increased compare to those of the control groups (P<0.05). The number of coli form bacteria was significantly reduced by feeding 0.3% or 0.5% SCE as compared to that of non-medication control (P<0.05). The results demonstrated that the SCE used in this study modulated humoral immunity and the profiles of cecal microflora and thus can be used as a potential alternative substance to replace antibiotics for feeding broiler chicks.

본 연구에서는 황금 추출물의 수준별 급여가 육계에서 성장 성적, 항체 생성 및 생리적 반응에 미치는 영향을 조사하였다. 1일령 Ross 육계 수평아리 750수를 실험동물로 공시하여 각 처리구별 150수, 반복 당 30수씩을 체중이 유사하도록 완전임의 배치하였고, 항생제를 첨가하거나 첨가하지 않은 기초사료에 황금 추출물을 0.1, 0.3 또는 0.5% 수준으로 각각 첨가하여 전체 5개 처리구에 5반복으로 구성하였다. 실험기간 중의 사료 섭취량, 증체량 및 사료 요구율을 평가하였고, 조직의 상대적 중량과 혈중 콜레스테롤 농도를 조사하였다. 생독백신 접종 이후의 체액성 면역반응에 미치는 영향과 맹장 내용물 내의 균총을 평가하였다. 황금 추출물 0.1% 및 0.3% 첨가구의 종료 시 체중과 증체량은 (-) 대조구에 비해 유의하게 높거나(P<0.05) 높은 경향을 나타내었다. 황금 추출물의 첨가급여로 인한 혈액 내 총 콜레스테롤, HDL-콜레스테롤 함량 및 HDL-C/total-C 비율에는 처리간에 유의한 차이가 없는 것으로 나타났다. NDV 항체가와 IBV 항체가는 대조구에 비해 황금 추출물 추출물을 급여한 모든 처리구에서 대조구에 비해 유의하게 증가하거나(P<0.05), 증가하는 경향을 나타내었다. 황금 추출물 첨가구에서 coli form 박테리아 수가 (-) 대조구에 비해 0.3% 및 0.5% 첨가구에서 유의하게 감소하거나(P<0.05), 감소하는 경향을 나타내었다. 결과적으로 황금 추출물의 첨가급여는 성장 개선 및 생리활성의 부여 측면에서 항생제 대체제로서의 활용 가능성이 매우 높은 것으로 판단되었다.

Keywords

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