Study on the Anti-tumor Effect of Gekko

천룡(天龍)의 항암효과에 대한 고찰

  • Ahn, Tae-Kyu (Liver-Immune Department of Oriental Medicine college, Daejeon University) ;
  • Son, Chang-Gue (Liver-Immune Department of Oriental Medicine college, Daejeon University) ;
  • Jeong, Tae-Yong (Liver-Immune Department of Oriental Medicine college, Daejeon University) ;
  • Yoo, Hwa-Seung (Liver-Immune Department of Oriental Medicine college, Daejeon University) ;
  • Cho, Jung-Hyo (Liver-Immune Department of Oriental Medicine college, Daejeon University)
  • 안태규 (대전대학교 한의과대학 간장 면역학 교실) ;
  • 손창규 (대전대학교 한의과대학 간장 면역학 교실) ;
  • 정태영 (대전대학교 한의과대학 간장 면역학 교실) ;
  • 유화승 (대전대학교 한의과대학 간장 면역학 교실) ;
  • 조정효 (대전대학교 한의과대학 간장 면역학 교실)
  • Published : 2009.12.28

Abstract

Gekko has been used for several diseases including cancer in Oriental medicine and fork herbalogy. Nevertheless, its origin as herbal medicine and its efficacy and mechanism as anti-tumor drug have not yet been thoroughly reported in Korea. This study aimed to investigate anti-tumor effect of Gekko through selected articles from cqvip database in China. In vitro and In vivo, Gekko could obviously inhibit tumor growth, induce tumor cells apoptosis, reduce micro-vessel density in tumor tissue through down regulating VEGF & bFGF protein expression, promote cytotoxicity of lymphocyte. Gekko could improve survival rate, relive clinical symptoms, improve quality of life, and relieve anti-tumor treatment reaction, suggesting that Gekko might be a effective anti-tumor drug.