Effects of Relative Swimming Exercise Intensity on mRNA Expression of UCP-1, UCP-3 Brown Adipose Tissue and Blood Insulin, and Glucose in Rat

상대적 수영운동 강도가 흰쥐 갈색지방조직의 UCP-1과 UCP-3 mRNA 발현, 혈중 인슐린 및 혈당에 미치는 효과

  • 윤진환 (한남대학교 생활체육학과) ;
  • 오명진 (한남대학교 생활체육학과) ;
  • 서태범 (한남대학교 생활체육학과) ;
  • 김종오 (한남대학교 생활체육학과) ;
  • 장문녀 (한남대학교 생활체육학과) ;
  • 박성태 (한남대학교 생활체육학과) ;
  • 김영표 (제주대학교 체육학과) ;
  • 유재현 (삼육대학교 사회복지학부)
  • Published : 2009.02.28


The purpose of this study was to investigate the UCP-1, UCP-3 mRNA expression in brown adipose tissue with glycometabolism according to intensity and duration of swimming in rat. F344 rat were randomly divided into three groups (n=10 in each group): control (CON), low-intensity swimming (LIS) groups, and high-intensity swimming (HIS) groups. Animals in the LIS group were forced to swim in swimming pool for 30min once a day for 8 consecutive weeks with a light intensity. In the HIS group, the rats repeated fifteen 20-s swimming bouts with a weight equivalent to 10% of body weight for 8weeks, respectively. The present result demonstrated that in LIS group, serum insulin and glucose levels significantly decreased in LIS group compared to CON. Brown adipose tissue UCP-1 and UCP-3mRNA expression was significantly increase in LIS group compared to CON and HIS groups. From those results, it can be suggested that low-intensity swimming may improve glycometablism control by up-regulating UCP-1 and UCP-3mRNA expression.


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