Association among Serum Lipid, Apolipoprotein Levels and Related Factors in Healthy Adults

중.장년층의 혈청 지질 및 아포지단백질의 농도와 관련된 요인 분석

  • Lee, Hoe-Seon (Dept. of Food and Nutrition, Gyeongsang National University) ;
  • Kim, Gyeong-Eup (Dept. of Food and Nutrition, Kyungnam University) ;
  • Park, Mi-Young (Dept. of Food and Nutrition, Gyeongsang National University) ;
  • Youn, Hee-Shang (Dept. of Pediatrics, Gyeongsang National University School of Medicine) ;
  • Choi, Sun-Young (Dept. of Home Economics Education, Gyeongsang National University) ;
  • Kim, Sung-Hee (Dept. of Food and Nutrition, Gyeongsang National University)
  • 이효선 (경상대학교 식품영양학과) ;
  • 김경업 (경남대학교 식품영양학과) ;
  • 박미영 (경상대학교 식품영양학과) ;
  • 윤희상 (경상대학교 의과대학 소아과교실) ;
  • 최선영 (경상대학교 가정교육학과) ;
  • 김성희 (경상대학교 식품영양학과)
  • Published : 2008.12.31

Abstract

This study was carried out to examine the association of age, nutrient intake, alcohol drinking and smoking on serum lipid and apolipoprotein levels in 100 healthy adults (54 males and 46 females). The serum total cholesterol, low density lipoprotein cholesterol (LDL-C) (p<0.05), apolipoprotein B (Apo B) levels, LDL-C:high density lipoprotein cholesterol (HDL-C) ratio, Apo B:apolipoprotein(Apo A-I) ratio and atherogenic index (AI) (p<0.001) were significantly higher in males than females, but HDL-cholesterol level was significantly lower (p<0.01) in males than females. The plasma ascorbic acid concentration had no difference in both genders. Most of nutrient intakes except Ca, vitamin A and vitamin $B_2$ were higher than RI (Recommended intake) in both males and females. The meal frequency per day was significantly higher (p<0.01) in males than females, while meal speed, the heaviest meal, meal quantity and meal regularity had no significant differences. The rates of drinking and smoking were significantly higher (p<0.01) in males (59.3%, 37.2%) than females (17.3%, 6.9%). The age was positively correlated with triglyceride level in males (p<0.05), and with total cholesterol (p<0.001), LDL-cholesterol (p<0.001), Apo B (p<0.01), LDL-C:HDL-C ratio (p<0.01), Apo B:Apo A-I ratio (p<0.05) and AI (p<0.01) in females. The levels of serum lipid and apolipoprotein were more correlated with protein intake than other macronutrient intakes in males, while those in females were more correlated energy, carbohydrate and lipid intakes than protein intake. The effect of drinking on serum lipid and apolipoprotein levels was bigger in males than females, while the effect of smoking on those was bigger in females than males. The plasma ascorbic acid concentration was positively correlated with HDL-cholesterol (p<0.05), Apo A-I levels (p<0.001), whereas negatively correlated with Apo B:Apo A-I ratio (p<0.05) in males. And that was positively correlated with HDL-cholesterol (p<0.05) in females. These results suggest that moderate macronutrient intake, less alcohol consumption and non-smoking were necessary to maintain healthy lipid profile with aging in adults.