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Discovery of Candidate SNP Related to Meat Quality Using the BcSNPdb and Cattle QTLdb in Hanwoo

한우에서 Cattle QTLdb와 BcSNPdb를 이용한 육질연관 후보 SNP 발굴

  • Kim, Dae-Hyun (Department of Animal Resources and Biotechnology Graduate School Yeungnam University) ;
  • Lee, Yoon-Seok (Department of Animal Resources and Biotechnology Graduate School Yeungnam University) ;
  • Oh, Young-Sook (Institute of Biotechnology Yeungnam University) ;
  • Choi, Chang-Bon (School of Biotechnology Yeungnam University) ;
  • Yeo, Jung-Sou (School of Biotechnology Yeungnam University)
  • 김대현 (영남대학교 대학원 동물생명과학과) ;
  • 이윤석 (영남대학교 대학원 동물생명과학과) ;
  • 오영숙 (영남대학교 생명공학연구소) ;
  • 최창본 (영남대학교 생명공학부) ;
  • 여정수 (영남대학교 생명공학부)
  • Published : 2008.12.31

Abstract

This study was aimed to find SNPs related with marbling score in Hanwoo(Korean cattle) using BcSNPdb. This study was searched QTL region related with marbling score and extracted 3,605 SNPs by applying BcSNPdb. Among these SNPs, 347 nonsynonymous SNP were selected and 160 SNPs were verified by PCR and finally proven with application to experimental data of the national progeny test. BTS_003888, BTS_012665 and BTS_009454 candidate SNPs were revealed significantly associated with marbling score(P<0.05), and BTS_025951 candidate SNPs was significantly associated with backfat thickness(P<0.05). From the result, SNPs from BTS_003888, BTS_009454, BTS_052584 and BTS_025951 were considered to be useful for the advancement in selective improved model in marbling score and backfat thickness of Hanwoo.

Keywords

References

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