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Analgesic and anti-inflammatory effect of the aqueous extract of root of Angelica Dahurica

  • Choi, In-Ho (Department of Rehabilitation Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Lim, Hyung-Ho (Department of Rehabilitation Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Song, Yun-Kyung (Department of Rehabilitation Medicine, College of Oriental Medicine, Kyungwon University) ;
  • Lee, Jin-Woo (Kohwang Medical Research Institute, Department of Physiology, College of Medicine, Kyung Hee University) ;
  • Kim, Young-Sick (Kohwang Medical Research Institute, Department of Physiology, College of Medicine, Kyung Hee University) ;
  • Ko, Il-Gyu (Kohwang Medical Research Institute, Department of Physiology, College of Medicine, Kyung Hee University) ;
  • Kim, Ki-Jeong (Kohwang Medical Research Institute, Department of Physiology, College of Medicine, Kyung Hee University) ;
  • Shin, Mal-Soon (Kohwang Medical Research Institute, Department of Physiology, College of Medicine, Kyung Hee University) ;
  • Kim, Khae-Hawn (Department of Urology, Gil Medical Center, Gachon University of Medicine and Science) ;
  • Kim, Chang-Ju (Kohwang Medical Research Institute, Department of Physiology, College of Medicine, Kyung Hee University)
  • Published : 2008.02.29

Abstract

Angelica dahurica (Umbelliferae) grows in China, Japan, Russia, and Korea. The root of Angelica dahurica has been used as a traditional folk medicine to treat headache and toothache. In this study, the effects of the aqueous extract of Angelica dahurica on acetic acid-induced abdominal pain, carrageenan-induced edema, and thermal hyperalgesia were investigated using mice and rats. The present results showed that the aqueous extract of Angelica dahurica inhibited acetic acidinduced abdominal pain in mice and reduced carrageen-induced edema in rats. The present study showed that the aqueous extract of Angelica dahurica possesses anti-inflammatory and analgesic effects.

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