Anti-oxidant Property and Tyrosinase Inhibition Activity of Various Extracts from plants in Compositae plants

국화류 추출물의 항산화 및 멜라닌 생성 억제 활성

  • Kang, Jeong-Ran (Department of Bioengineering at the Postgraduate School, Konkuk University) ;
  • Lee, Mi-Kyung (Department of Pharmaceutical Engineering, Woosuk University) ;
  • Kang, Sang-Mo (Department of Bioengineering at the Postgraduate School, Konkuk University)
  • 강정란 (건국대학교 대학원 생물공학과) ;
  • 이미경 (우석대학교 제약공학과) ;
  • 강상모 (건국대학교 대학원 생물공학과)
  • Published : 2008.12.31


The research was conducted to identify the antimicrobial effect, anti-oxidative effect and tyrosinase inhibitory effect of MeOH 80% extract and n-hexane, chloroform, ethyl acetate, n-butanol and water fractions from the extract of six kinds of compositae plants, which are naturally grown across the nation. In the antimicrobial effect, the extract and chloroform fraction of Arctium lappa and hexane/ethyl acetate fractions of Taraxacum platycarpum exhibited significant inhibition. In case of antioxidant effect, the extract of Artemisia capillaries showed the highest effect and ethyl acetate/butanol fractions of all plants showed about 90%, which fractions were more polar than the fractions that showed antimicrobial effect. In case of tyrosinase activity, only the MeOH 80% of Arctium lappa among the extracts showed a potent inhibition, and butanol fraction of Chrysanthemum indicum, as well as ethyl acetate/water fractions of Artemisia capillaries showed 48, 38, and 37% respectively, which were higher than control group (arbutin). These active fractions in tyrosinase inhibition also were higher polarity than those that showed antimicrobial effect. In MeOH 80% extracts, only Arctium lappa was found to have antimicrobial, anti-oxidant and tyrosinase inhibitory activity, however there was no fraction to show effects commonly in the three assay system.


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