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Search Method for Consensus Pattern of Transcription Factor Binding Sites in Promoter Region

프로모터 영역의 전사인자 결합부위 Consensus 패턴 탐색 방법

  • 김기봉 (상명대학교 공과대학 생명정보공학과)
  • Published : 2008.10.31

Abstract

Located on the upstream of a gene, the promoter region that plays a very important role in the control of gene expression as a signal part has various binding sites for transcription factors. These binding sites are present in various parts of the promoter region and assume an aspect of highly conserved consensus sequence pattern. This paper deals with the introductions of search methods for consensus pattern, including Wataru method, EM algorithm, MEME algorithm, Genetic algorithm and Phylogenetic Footprinting method, and intends to give future prospects of research on this field.

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