Comparisons of UCP2 Polymorphism, Dietary Habits, and Obesity Index in Normal and Obese University Students

정상체중과 비만인 대학생의 UCP 2 유전자 다형성, 식습관, 비만도 및 체성분의 비교 연구

  • Ahn, Myoung-Soo (Gwangju Samsung Medical Center) ;
  • Chang, In-Youb (Korea DNA Repair Research Center Dept of Anatomy, School of Medicine, Chosun University) ;
  • Kim, Kyung-Hee (Food and Nutrition, Division of Human Ecology, Mokpo National University)
  • Published : 2007.09.30

Abstract

This study was carried out to compare UCP2 polymorphism, dietary habits, and obesity index in normal and obese university students. The survey was carried out using self-questionnaires collected from the 126 normal and 60 obese university students. The results are summarized as follows. Breakfast was skipped in 43.7% of normal and 49.3% of obesity students and it appeared obese students eat faster than normal students. The percentage of weight control experience were 49.2 and 71.0 in the normal and obese students, respectively. Blood levels of lipid profiles(triglyceride, LDL cholesterol, and HDL cholesterol), hemoglobin, AST and ALT were anaylzed. In UCP2 genes, the frequency of deletion homozygote(DD) was 71.5%, heterozygote(DI) was 26.9% and insertion homozygote(II) was 1.6%. Plasma levels of triglyceride, total cholesterol, LDL cholesterol, and HDL cholesterol of normal students were 79.06, 172.25, 100.86 and 57.03 mg/dl, and those of obese students were 93.06, 173.22, 101.22 and 54.39 mg/dl, respectively. Blood parameters were in normal range in both group. Plasma triglyceride, total cholesterol and LDL cholesterol levels of obese students were higher than those of normal students. On the other hand, plasma HDL cholesterol levels of obese students were lower than those of normal students. Plasma levels of AST and ALT were in normal range in both group. However, AST and ALT levels of obese students were higher than that of normal students. Thus, it was recommended for them to have a nutritional education program to improve their dietary and living habits for obese students’health. Nutritional education program should also be organized practically and systematically.

Keywords

UCP2 polymorphism;dietary habits;nutritional education

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