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Effect of Dietary Krill Meal Levels on the Cell Mediated Immunity in Intra-muscularly Croton Oil Injected Broiler Chicks

파두유를 주입한 육계병아리에서 사료중 크릴밀 수준이 세포성 면역에 미치는 영향

  • Im, J.T. (Department of Animal Life Sciences, College of Animal Life Sciences, Konkuk University) ;
  • Park, I.K. (Department of Animal Life Sciences, College of Animal Life Sciences, Konkuk University) ;
  • Koh, T.S. (Department of Animal Life Sciences, College of Animal Life Sciences, Konkuk University)
  • 임진택 (건국대학교 동물생명과학대학 동물생명과학부) ;
  • 박인경 (건국대학교 동물생명과학대학 동물생명과학부) ;
  • 고태송 (건국대학교 동물생명과학대학 동물생명과학부)
  • Published : 2007.10.31

Abstract

Effect of dietary krill meal levels on the cellular immunity was studied in broiler chicks activated immune response. One day old male broiler chicks(Ross) were fed the experimental krill meal 0.0(basal), 0.5, 1.0 and 2.0% diets for 3wks. Blood TNF-α activity, ovotransferrin level and Con A induced proliferation of PBMC and splenocytes after 24 hr(21 d age) of the croton oil 10㎕ injection intra- musculary at the age of 20 days compared to the control olive oil. Krill meal diets did not affect growth performance of broiler chicks and plasma ovotransferrin levels but decreased significantly(p<0.0001) TNF-α like activity and proliferation of PBMC relative to krill meal 0.0% diet. And the proliferation of splenocytes were significantly(p<0.05) increased in birds fed krill meal 1.0% diet relative to krill meal 0.5 and 2.0% diets. The croton oil injection induced a significant(p<0.0001) increases in the TNF-α activity or the PBMC proliferation and enhanced circulating ovotransferrin levels relative to the olive oil. In birds injected with the croton oil the proliferation of PBMC was reduced linearly with the increase of dietary krill meal levels, and the proliferation of splenocytes was decreased in the krill meal 1.0 and 2.0% diets relative to olive oil. These results indicated that dietary krill meal changed the innate and cellular immunity in broiler chicks activated by the injection of croton oil.

Keywords

Croton oil;Tumor necrosis factor-a(TNF-a);Proliferation of PBMC and splenocytes;Krill meal;Broiler chicks

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