Effects of Sex Steroid Hormones on Differentiation of Pig Preadipocytes

스테로이드 성호르몬이 돼지 지방전구세포의 분화에 미치는 영향

  • Kim, H.R. (Department of Animal Science, Chungbuk National University) ;
  • Lee, K.H. (Department of Biochemistry and Molecular Biology and Center of Antiaging, Eulji University) ;
  • Choi, I.H. (School of Biotechnology, Yeungnam University) ;
  • Chung, C.S. (Department of Animal Science, Chungbuk National University)
  • Published : 2007.10.31


The current study was undertaken to determine the effects of sex steroid hormones(estrogen, testosterone and 19-nortestosterone) on differentiation and proliferation of pig preadipocytes. The preadipocytes were isolated from the backfat of new-born female pigs by collagenase digestion. 10-8M and 10-7M sex steroid hormones were treated to the cultured preadipocytes. Sex steroid hormones treated during the early stage of cell growth did not affect differentiation and proliferation of preadipocytes. However, testosterone and 19- nortestosterone treated during the late stage of cell growth stimulated differentiation of pig preadipocytes.


Sex steroid;Pig;Preadipocytes;Differentiation


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