Preparation of Vesicles Using Octasubstituted Cyclotetraphosphazene

Octasubstituted Cyclotetraphosphazene으로부터 Vesicle의 형성

  • Shin, Young Jae (Department of Electrical Engineering and Computer Science, KAIST) ;
  • Park, Chul Soon (Department of Chemistry and Basic Sciences Research Institute, Chungbuk National University) ;
  • Kim, Ju Youn (Department of Chemistry and Basic Sciences Research Institute, Chungbuk National University) ;
  • Kim, Se Ra (Department of Chemistry and Basic Sciences Research Institute, Chungbuk National University) ;
  • Shin, Jae Sup (Department of Chemistry and Basic Sciences Research Institute, Chungbuk National University)
  • 신영재 (한국과학기술원 전자전산학과) ;
  • 박철순 (충북대학교 화학과.기초과학연구소) ;
  • 김주연 (충북대학교 화학과.기초과학연구소) ;
  • 김세라 (충북대학교 화학과.기초과학연구소) ;
  • 신재섭 (충북대학교 화학과.기초과학연구소)
  • Received : 2006.10.26
  • Accepted : 2007.01.25
  • Published : 2007.02.10

Abstract

A cyclotetraphosphazene derivative having eight chains was synthesized from octachlorocyclotetraphosphazene, which was employed along with cholesterol for the preparation of vesicles. The resulting vesicles were characterized by TEM and encapsulation efficiency. The stability of the vesicles was enhanced in the presence of dihexadecylphosphate.

Acknowledgement

Supported by : 중소기업청

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