- Volume 20 Issue 2
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Association of SNP Marker in the Thyroglobulin Gene with Carcass and Meat Quality Traits in Korean Cattle
- Shin, S.C. (Division of Animal Science and Resources, College of Life Science and Natural Resources Sangji University) ;
- Chung, E.R. (Division of Animal Science and Resources, College of Life Science and Natural Resources Sangji University)
- Received : 2006.04.07
- Accepted : 2006.08.22
- Published : 2007.02.01
Thyroid hormones play an important role in regulating metabolism and can affect homeostasis of fat depots. The gene encoding thyroglobulin (TG), producing the precursor for thyroid hormones, has been proposed as a positional and functional candidate gene for a QTL with an effect on fat deposition. The SNP occurs in the 5' promoter region of the TG gene and is widely used in marker assisted selection (MAS) programs to improve the predictability of marbling level and eating quality in beef cattle. In this study, we identified three SNPs at the 5' promoter region of the TG gene in Korean cattle. Of the three SNPs identified in TG gene, the C257T and A335G were previously unreported new SNPs. The sequence data were submitted to GenBank (GenBank accession number: AY615525). The previously reported C422T SNP showed three genotypes, CC, CT and TT, by digestion with the restriction enzyme MflI using the PCR-RFLP method. A new allelic variant corresponding to the C
Supported by : Rural Development Administration
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- Association of polymorphisms in the leptin and thyroglobulin genes with meat quality and carcass traits in beef cattle vol.41, pp.10, 2012, https://doi.org/10.1590/S1516-35982012001000004
- Exploring evidence of positive selection reveals genetic basis of meat quality traits in Berkshire pigs through whole genome sequencing vol.16, pp.1, 2015, https://doi.org/10.1186/s12863-015-0265-1
- Effect of thyroglobulin gene polymorphisms on growth, carcass composition and meat quality traits in Chinese beef cattle vol.42, pp.9, 2015, https://doi.org/10.1007/s11033-015-3919-1