Establishment acceptable daily intakes(ADIs) for pesticides registered in Korea

국내등록농약의 일일섭취허용량(ADI) 설정

  • Lee, Je-Bong (National Institute of Agricultural Science and Technology) ;
  • Shin, Jin-Sup (National Institute of Agricultural Science and Technology) ;
  • Park, Yeon-Ki (National Institute of Agricultural Science and Technology) ;
  • You, Are-Sun (National Institute of Agricultural Science and Technology) ;
  • Hong, Soon-Sung (National Institute of Agricultural Science and Technology) ;
  • Im, Gun-Jae (National Institute of Agricultural Science and Technology) ;
  • Kang, Kyu-Young (Dept. of Environ. Biotechnology, Gyeong Sang National University)
  • 이제봉 (농촌진흥청 농업과학기술원) ;
  • 신진섭 (농촌진흥청 농업과학기술원) ;
  • 박연기 (농촌진흥청 농업과학기술원) ;
  • 유아선 (농촌진흥청 농업과학기술원) ;
  • 홍순성 (농촌진흥청 농업과학기술원) ;
  • 임건재 (농촌진흥청 농업과학기술원) ;
  • 강규영 (경상대학교 환경생명화학과)
  • Published : 2007.12.30


In order to set ADIs for pesticides registered for use in Korea, an analysis of guidelines on setting ADIs and ADIs established by international bodies and advanced countries was conducted General guidelines on the derivation ADIs are very similar among regulatory authorities. However, there were large differences in the ADIs' setting status and ADI values set for some individual pesticides. ADIs were established for 213 pesticides in UN, 332 in USA, 230 in Japan, 219 in UK and 435 in EU and Australia. Of the established ADIs in other countries, 87 to 252 pesticides were the pesticides registered in Korea depending countries. The number of lowest ADIs depending countries was 32 in USA, 23 in Japan, 6 in EU and Australia. The key target organs and endpoints used for setting ADIs were in the order of enzyme inhibition, body weight change and adverse effect on liver. The number of ADIs used for setting MRLs in Korea was high in the order of JMPR, Japan and USA. ADIs of EU and JMPR had highest similarity among bodies investigated. By referring to the guidances investigated at this study, guideline for setting ADI and ADIs for 64 pesticides registered in Korea were proposed.


Pesticide;Risk assessment;ADI


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