Effect on antioxidant function of onion to reduce pesticides toxicity

양파의 항산화기능을 이용한 농약 독성경감 효과

  • You, Are-Sun (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • Jeong, Mi-Hye (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • Park, Kyung-Hun (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • Kim, Byung-Seok (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • Lee, Je-Bong (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • Choi, Ju-Hyeon (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • Kwon, Oh-Kyung (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • Kim, Jin-Hwa (National Institute Crop Science)
  • 유아선 (농업과학기술원 농산물안전성부) ;
  • 정미혜 (농업과학기술원 농산물안전성부) ;
  • 박경훈 (농업과학기술원 농산물안전성부) ;
  • 김병석 (농업과학기술원 농산물안전성부) ;
  • 이제봉 (농업과학기술원 농산물안전성부) ;
  • 최주현 (농업과학기술원 농산물안전성부) ;
  • 권오경 (농업과학기술원 농산물안전성부) ;
  • 김진화 (농촌진흥청 작물과학원)
  • Published : 2007.12.30

Abstract

It is well known the functional foods are very useful to prevent serious diseases and promote health. Therefore, they are often called as nutraceuticals, designer foods, and pharmafoods, etc. Most of foods have diverse functions because they provide nutrients, energies and fibrinoid materials. When foods are taken in the body, they promote the biological defense system against diseases through the supply of the essential or healthy materials to human being's organs. The mode of action and functional foods in human body have not been clarified yet. Antioxidant is known as one of the therapeutic aids which can be reduced pesticide poisoning. Onion has a strong antioxidant effect. This study was carried out to elucidate an antioxidant function of onion by determination of superoxide dismutase in liver, lung, serum of male rat administered by intraperitonial injection of 0, 2, $4\;mg\;kg^{-1}$ cblorpyrifos after administrated orally with onion for 6 weeks. Damage of liver and kidney was also investigated by biochemical analysis of serum(AST, ALT, BUN/Creatine ratio). SOD(superoxide dismutase) activity of onion-administrated group is higher than control group. In liver and lung, SOD activity of onion+cblorpyrifos administrated group is higher than only chlorpyrifos administrated group. BUN/Creatinine ratio of onion+chlorpyrifos administrated group was decreased compared with only chlorpyrifos-administrated group.

Keywords

onion;chlorpyrifos;SOD activity;functional foods

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