Distribution of the fungicide hexaconazole in internal organs of carp (Cyprinus carpio L.)

살균제 hexaconazole의 잉어(Cyprinus carpio L.) 장기 중 분포

  • Lee, Eun-Young (School of Applied Life Science and Environment, College of Agriculture, Life and Environmental Sciences, Chungbuk National University) ;
  • Park, In-Young (School of Applied Life Science and Environment, College of Agriculture, Life and Environmental Sciences, Chungbuk National University) ;
  • Kim, Byung-Seok (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • Park, Yeon-Ki (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • You, Oh-Jong (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • Park, Kyung-Hun (Department of Crop Life Safety, National Institute of Agricultural Science & Technology) ;
  • Kim, Kyun (Analytical Research Center, Korea Institute of Toxicology) ;
  • Kyung, Kee-Sung (School of Applied Life Science and Environment, College of Agriculture, Life and Environmental Sciences, Chungbuk National University)
  • 이은영 (충북대학교 농업생명환경대학 응용생명환경학부) ;
  • 박인영 (충북대학교 농업생명환경대학 응용생명환경학부) ;
  • 김병석 (농업과학기술원 농산물안전성부) ;
  • 박연기 (농업과학기술원 농산물안전성부) ;
  • 유오종 (농업과학기술원 농산물안전성부) ;
  • 박경훈 (농업과학기술원 농산물안전성부) ;
  • 김균 (한국화학연구원 부설 안전성평가연구소 분석시험센타) ;
  • 경기성 (충북대학교 농업생명환경대학 응용생명환경학부)
  • Published : 2007.12.30

Abstract

In order to elucidate the behavior of the fungicide hexaconazole (1-(6-chloro-3-pyrldyhnethyl)N-nitroimidazolidin-2-ylideneamine) in carp (Cyprinus carpio L.), carps were exposed to [$^{14}C$]hexaconazole at a predicted environmental concentration (PEC) of 0.32 mg $L^{-1}$ for 4 days under static conditions. Hexaconazole in water was absorbed into carps to reach the maximum concentration 2 days after exposure. The amounts of the [$^{14}C$]hexaconazole and its metabolites absorbed in gall were much higher than those in the other organs and especially those in gall 2 days after exposure were 25 and 67 times higher than those in liver and kidney, respectively, strongly suggesting that biliary excretion involving enterohepatic recirculation could be an import route for the elimination of hexaconazole absorbed in carps.

Keywords

hexaconazole;carp;behavior;enterohepatic recirculation

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