Imprint Cytology of Granular Cell Tumor -A Case Report-

과립세포종양의 압착도말 세포학적 소견 -1예 보고-

  • Sung, Woo-Jung (Department of Pathology Yeungnam University College of Medicine) ;
  • Choi, Joon-Hyuk (Department of Pathology Yeungnam University College of Medicine)
  • 성우정 (영남대학교 의과대학 병리학교실) ;
  • 최준혁 (영남대학교 의과대학 병리학교실)
  • Published : 2007.09.30


Granular cell tumor is a rare tumor of the soft tissue and this is characterized by proliferation of large cells with granular appearing eosinophilic cytoplasm. We report the imprint cytologic features of a case of granular cell tumor in the left calf of a 52-year-old woman. Microscopic examination showed moderate cellularity. The tumor cells were arranged both as single cells and in clusters. The cells were large polygonal-shaped and they had small round nuclei with finely granular chromatin and occasionally conspicuous nucleoli. The cytoplasm was abundant eosinophilic and granular. Naked nuclei and spindle-shaped tumor cells were occasionally noted. No mitosis and necrosis were present. The background showed cytoplasmic granular materials. The tumor cells showed positivity for S-100 protein. Ultrastructurally, abundant lysosomes were present in the cytoplasm of the tumor cells.


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