The Antimicrobial Activity against Helicobacter pylori and Antioxidant effect from the extracts of Mulberry leaves (Morus Alba L.)

품종이 다른 뽕잎추출물의 Helicobacter Pylori에 대한 항균활성 탐색과 항산화 효과

  • Cho, Young-Je (Department of Food Engineering, Sangju National University) ;
  • Ju, In-Sik (Department of Food Engineering, Sangju National University) ;
  • Kim, Byung-Oh (Department of Applied Biology, Sangju National University) ;
  • Kim, Jeung-Hoan (NIP Biotech.) ;
  • Lee, Byung-Gu (Department of Culinary & Bakery, Yuengnam Foreign Language College) ;
  • An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Choo, Jae-Weon (Sericulture & Entomology Experiment Station, Gyeongbuk Agricultural Technology Administration)
  • 조영제 (상주대학교 식품공학과) ;
  • 주인식 (상주대학교 식품공학과) ;
  • 김병오 (상주대학교 생물응용학과) ;
  • 김정환 ;
  • 이병구 (영남외국어대학 호텔조리제빵과) ;
  • 안봉전 (대구한의대학교 화장품약리학과) ;
  • 추재원 (경상북도농업기술원 잠사곤충사업장)
  • Published : 2007.12.31

Abstract

The water extracts and 80% ethanol extracts from mulberry leaves of 108 kinds were tested their antimicrobial activities against Helicobacter pylori and antioxidant effects. The ABTS [2,2'-azino-bis(3-ethylbenzothiaznoline-6-sulfornic acid)] radical decolorization, electron donating ability (EDA), thiobarbituric acid reactive substance (TBARS) and antioxidant protection factor (PF) were determined for water extracts and 80% ethanol extracts from mulberry leaves. In the electron donating activity, the 13 kinds of water extracts showed high inhibition (>80%), whereas the 59 kinds of 80% ethanol extracts showed high inhibition. The inhibitory activities of water extracts from all kinds of mulberry leaves were higher than 90% in ABTS [2,2'-azinobis(3-ethylbenzothiaznoline-6-sulfornic acid)] radical decolorization. The thiobarbituric acid reactive substance (TBARS) and antioxidant protection factor (PF) of the 80% ethanol extracts were higher than that of water extracts. Antimicrobial activity against Helicobacter pylori showed high value in 80% ethanol extracts of 15 kinds mulberry leaves. The results implied that the mulberry leaves can be useful for natural antimicrobial medicine.

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