Phytotoxin Isolated from the Culture Broth of Chaetomium sp.

Chaetomium sp. 배양액에서 분리한 논피의 유근 저해물질

  • Lim, Chi-Hwan (Department of Bioenvironmental Chemistry, College of Agricultural & Life Sciences, Chungnam National University) ;
  • Kim, Mi-Young (Department of Bioenvironmental Chemistry, College of Agricultural & Life Sciences, Chungnam National University) ;
  • Lee, Jae-Won (Department of Bioenvironmental Chemistry, College of Agricultural & Life Sciences, Chungnam National University) ;
  • Yun, Bong-Sik (Korea Research Institute of Bioscience and Biotechnology) ;
  • Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
  • 임치환 (충남대학교 농업생명과학대학 생물환경화학) ;
  • 김미영 (충남대학교 농업생명과학대학 생물환경화학) ;
  • 이재원 (충남대학교 농업생명과학대학 생물환경화학) ;
  • 윤봉식 (한국생명공학연구원 항산화소재연구실) ;
  • 백승화 (원광대학교 한의학전문대학원 한약자원개발학과)
  • Published : 2007.12.31

Abstract

Three phytotoxic compounds were isolated from the culture broth of Chaetomium sp. through silica gel column chromatography and HPLC (RP-18). Their chemical structures were elucidated as chaetoglobosin F, chaetoglobosin C and chaetoglobosin E on the basis of instrumental analyses such as $^1H-NMR,\;^{13}C-NMR$, and HMQC. They inhibited the root growth of barnyard grass with the $IC_{50}$ values of 66, 65, and $67{\mu}g/ml$, respectively.

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