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Effects of Acanthopanax senticosus Extract on Macrophage Activity and the Growth of Lactic Starter Culture during Fermentation

가시오가피 추출물이 마크로파지 활성과 우유의 발효 중 젖산균 성장에 미치는 영향

  • Published : 2007.12.30

Abstract

We examined the effect of Acanthopanax senticosus extract on macrophage activity and its effect on the growth of lactic starter culture when added to fermented milk. Greater amounts of Acanthopanax senticosus extract correlated with higher macrophage activity (p<0.05), in particular at $1,000\;{\mu}g/mL$. Water extract of Acanthopanax senticosus resulted in higher levels of nitric oxide (NO) than 70% ethanol extract at $1,000\;{\mu}g/mL$. In contrast, 70% ethanol extract resulted in higher $interleukin-1{\alpha}\;(IL-1{\alpha})$ and Tumor necrosis $factor-{\alpha}\;(TNF-{\alpha})$ levels than water extract. The growth of lactic starter culture was inhibited by increasing amounts of Acanthopanax senticosus water extract, resulting in a lower decrease in pH. A stirred type or drink type fermentation process seemed more suitable than a set type for the proper production of Acanthopanax senticosus extract added to fermented milk.

Keywords

Acanthopanax senticosus;macrophage activity;growth;lactic starter culture

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