Antibacterial Effects of Oriental Herb Extract Against Gardnerella vaginalis

Gardnerella vaginalis에 대한 한약재의 항균활성

  • Kim Youn-Hee (Department of Oriental Medicine, Semyung University) ;
  • Lee Heung-Shick (Department of Biotechnology and Bioinformatics, Korea University)
  • Published : 2006.03.01

Abstract

To investigate the potential of treatment, antimicrobial activity of various oriental herb extracts were tested for Gardnerella vaginalis, which is the predominant organism in bacterial vaginosis. Among the tested 14 oriental herbs, water-extracts of Kalkeun, Kosam, Nuro, Pakjakyak, Sukchangpo, Shiyup, Junghyang and Hwangryun represented antibacterial activities against G. vaginalis. The minimal inhibition concentration (MIC) of Shiyup against G. vaginais was 0.63 mg/mL, and those of Pakjakyak and Hwangryun, Kalkeun and Nuro, Kosam, Sukchangpo and Junghyang were 1.25 mg/mL, 2.5 mg/mL, and 5 mg/mL, respectively. There-fore, the water-extracts of Kalkeun, Kosam, Nuro, Pakjakyak, Sukchangpo, Shiyup, Junghyang and Hwangryun were considered to be potential treatment of bacterial vaginosis caused by G. vaginalis.

Keywords

Antibacterial effect;bacterial vaginosis;Gardnerella vaginalis

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