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Current Research Status for Economically Important Candidate Genes and Microarray Studies in Cattle

소의 경제형질 관련 후보 유전자 및 Microarray 연구현황

  • 유성란 (충남대학교 농업생명과학대학 동물자원과학부) ;
  • 이준헌 (충남대학교 형질전환복제돼지연구센터)
  • Published : 2006.04.30

Abstract

Researches in livestock are currently actively progressing to improve economically important traits using DNA markers. In cattle, the candidate genes have been selected based on their known functions in the target QTL (quantitative trait locus) region in order to identify QTN (quantitative trait nucleotide) for improving productivities. In this review, molecular genetic studies for the meat related traits, one of the major determinant of market prices, have been fully described. Also recent emerging microarray technique for identifying candidate genes in cattle has been discussed. In case of microarray, cDNA microarrays have been replaced to oligoarrays in order to minimize the experimental errors in cattle. Since the first draft of bovine genome sequences was appeared in the public domain, more markers in relation to the quantitative traits will be discovered in a short period of time and genes affecting difficult-to-measure traits, such as disease resistance, can also be selected for marker assisted selection in near future.

Keywords

Candidate genes;Cattle;DNA marker;Microarray;Quantitative trait locus

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